Evaluation of Plasma Non-coding RNAs as Biomarkers in Coronary Heart Disease

NCT ID: NCT02751060

Last Updated: 2024-04-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

4000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-04-30

Study Completion Date

2026-12-31

Brief Summary

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The purpose of this study is to determine whether the expression level of miR-320a are effective as biomarker in evaluating the diagnosis, prognosis and treatment effects of coronary heart disease.

Detailed Description

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Conditions

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Coronary Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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patients with coronary heart disease symptoms

No intervention

Intervention Type OTHER

Interventions

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No intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. 18 years of age or older;
2. the most recent symptoms of coronary heart disease within 7 days;
3. meet one of the following conditions: A. clinical history of typical ischemic chest pain (more than 5 minutes of persistent chest pain); B. serum cardiac biomarkers positive (TnT/I or creatine kinase peak greater than 99% of URL); C. Electrocardiogram changes of myocardial ischemia.

Exclusion Criteria

1. pregnant women or plan to;
2. participate in any drug clinical trials within 3 months;
3. patients with life-threatening complications, or the researchers determined that the survival time of patients with no more than 1 years;
4. serious neurological disease (Alzheimer's disease, Parkinson syndrome, progressive lower limbs or deaf patients);
5. previous history of cancer or tumor, or pathological examination confirmed precancerous lesions (such as breast ductal carcinoma in situ, or atypical hyperplasia of the cervix);
6. patients refused to comply with the requirements of this study to complete the research work;
7. according to the researchers, patients can not complete the study or not to comply with the requirements of this study (because of the reasons for the management or other reasons).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Tongji Hospital

OTHER

Sponsor Role lead

Responsible Party

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Dao Wen Wang

Prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Dao Wen Wang, Doctor

Role: PRINCIPAL_INVESTIGATOR

Tongji Hospital

Locations

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Tongji Hospital

Wuhan, Hubei, China

Site Status

Countries

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China

Other Identifiers

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TJ-IRB20160305

Identifier Type: -

Identifier Source: org_study_id

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