Serotonin, Leptin and Adiponectin Level in Patients With Postpartum Depression: Controlled Study

NCT ID: NCT02682004

Last Updated: 2022-03-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-02-29

Study Completion Date

2017-05-31

Brief Summary

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After vaginal delivery, all of the participants will evaluate by using Edinburg depression scale and venous blood sample will obtain. Postpartum depression will consider the result of scale 13 and above according to Turkhish translate. Then leptin, adiponectin and serotonin level will compare between depressed and nondepressed women.

Detailed Description

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Conditions

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Postpartum Depression

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Women with postpartum depression

leptin, serotonin and adiponectin level

Intervention Type OTHER

Women without postpartum depression

leptin,serotonin, adiponectin level

Intervention Type OTHER

Interventions

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leptin, serotonin and adiponectin level

Intervention Type OTHER

leptin,serotonin, adiponectin level

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* All women who gave birth

Exclusion Criteria

* women with previously diagnosed depression and any psychiatric disorders
* women with previously take antidepressan and antipshycothic
* women giving birth to children with anomalies
* women with undertake surgery for peripartum hemorrhage
Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Zeynep Kamil Maternity and Pediatric Research and Training Hospital

OTHER

Sponsor Role lead

Responsible Party

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Mehmet Baki Senturk

Principal investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Zeynep Kamil Maternity and Pediatric Research and Training Hospital

Istanbul, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Hu Y, Dong X, Chen J. Adiponectin and depression: A meta-analysis. Biomed Rep. 2015 Jan;3(1):38-42. doi: 10.3892/br.2014.372. Epub 2014 Oct 16.

Reference Type RESULT
PMID: 25469244 (View on PubMed)

Skalkidou A, Sylven SM, Papadopoulos FC, Olovsson M, Larsson A, Sundstrom-Poromaa I. Risk of postpartum depression in association with serum leptin and interleukin-6 levels at delivery: a nested case-control study within the UPPSAT cohort. Psychoneuroendocrinology. 2009 Oct;34(9):1329-37. doi: 10.1016/j.psyneuen.2009.04.003. Epub 2009 May 7.

Reference Type RESULT
PMID: 19427131 (View on PubMed)

Mansur RB, Rizzo LB, Santos CM, Asevedo E, Cunha GR, Noto MN, Pedrini M, Zeni M, Cordeiro Q, McIntyre RS, Brietzke E. Adipokines, metabolic dysfunction and illness course in bipolar disorder. J Psychiatr Res. 2016 Mar;74:63-9. doi: 10.1016/j.jpsychires.2015.12.003. Epub 2015 Dec 12.

Reference Type RESULT
PMID: 26748249 (View on PubMed)

Related Links

Other Identifiers

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51

Identifier Type: -

Identifier Source: org_study_id

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