Risk of Maternal Depression From 1 Year to 4 Years Postpartum in Yvelines

NCT ID: NCT06042972

Last Updated: 2024-03-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

800 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-09-30

Study Completion Date

2024-10-30

Brief Summary

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This observational study aims to estimate the prevalence of women from 1 to 4 years postpartum in Yvelines, who are suspected to suffer from postpartum depression, using the Edinburg Post natal Depression Scale (EPDS) and the Patient Heath Questionnaire 2 (PHQ2) and evaluate the factors that could be linked to it.

Detailed Description

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The majority of studies and literature on maternal psychology focus on mothers of infants and newborns. The psychological experience of mothers with older children is still yet to be one of the subjects covered in the research on maternal psychology.

Postpartum depression characterizes itself in a depressive episode without psychotic characteristics, where symptoms appear in the year following delivery.

These symptoms reach their peak between 3 and 6 weeks postpartum. The diagnosis of postpartum depression is made by health professionals with the help of questionnaires such as the Edinburgh Postnatal Depression Scale (EPDS) or the Patient Health Questionnaire 2 (PHQ2).

According to the last national perinatal survey from Santé Publique France (Edition 2021), the rate of women having postpartum depression was estimated at 16.7%.

In France, the current psychological follow-up exam for women after giving birth includes a postnatal interview which is systematically offered between the 4th and the 8th week after delivery. It can be followed by another interview between the 10th and 14th week postpartum if judged necessary by the healthcare provider. It can also be offered by request.

Currently, there are no screening consultations for postpartum depression beyond the 14th week postpartum. Health care professionals are trained to be vigilant in the 1st year postpartum but not beyond this time frame.

A multicentric Australian study based on 1,507 women described the prevalence of maternal depression from early pregnancy to 4 years postpartum. It also covered the risk factors for depressive symptoms at 4 years postpartum.

The study concluded that maternal depression is more common at 4 years postpartum than at any time in the first 12 months postpartum. The prevalence of depressive symptoms at 4 years postpartum was 14.5% which was higher than at any time-point in the first 12 months post partum.

Currently, no French study focuses on the number of women suffering from maternal depression beyond 12 months postpartum.

This study aims to assess the prevalence of women 1 to 4 years postpartum who are suspected to have maternal depression and its linked factors.

Depression in one's lifetime can lead to negative consequences on a mother's psychological health and her quality of life, as well as her children's health.

The impact on children can include physical or mental developmental delay, regressed cognitive or language development, and general infant health issues.

Thus, if this study shows a significant risk for women to develop delayed maternal depression, extending a psychological follow-up exam of women beyond the 1st year postpartum could be necessary.

Moreover, screening and treating these women could limit the consequences on their children's development and well-being.

Conditions

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Post Partum Depression

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Interventions

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Questionnaire including Edinburgh postnatal depression scale, Patient Health Questionnaire 2 and background variables

Patients meeting the inclusion criteria will be recruited by health professionals who have agreed to participate in the study.

Patients must fill out an anonymous self-questionnaire which will consist of 2 tests aimed to help diagnose postpartum depression, recommended in France by the Haute Autorité de Santé (HAS), and background variables.

The self-questionnaire will be given back by the patient in a sealed envelope. Each questionnaire will only be filled out once per patient.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Women over 18 years old
* Women from 1 year to 4 years postpartum or having children aged from 1 to 4 years old
* Patient gave their consent to participate in the study
* Patient lives in Yvelines
* Patient speaks and understands French
* Patient reads and writes in French

Exclusion Criteria

* Patient suffered from postpartum depression in the 1st year after giving birth or is currently being treated for postpartum depression that started showing symptoms in the 1st year after giving birth.
* Patient is currently pregnant
* Patient gave birth less than 1 year prior or more than 4 years prior; or has a child who is less than one year old; or 5 or more years old
* Patient didn't give her consent to participate in the study
* Patient is under guardianship or judicial safeguard
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Centre Médical Porte Verte

OTHER

Sponsor Role lead

Responsible Party

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Cyriane Courtois

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Hôpital de la Porte Verte

Versailles, Île-de-France Region, France

Site Status RECRUITING

Countries

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France

Central Contacts

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Cyriane COURTOIS-B, DR

Role: CONTACT

0139543712 ext. +33

Fatima IZEDAREN, CRA

Role: CONTACT

0139637451 ext. +33

References

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Woolhouse H, Gartland D, Mensah F, Brown SJ. Maternal depression from early pregnancy to 4 years postpartum in a prospective pregnancy cohort study: implications for primary health care. BJOG. 2015 Feb;122(3):312-21. doi: 10.1111/1471-0528.12837. Epub 2014 May 21.

Reference Type BACKGROUND
PMID: 24844913 (View on PubMed)

Slomian J, Honvo G, Emonts P, Reginster JY, Bruyere O. Consequences of maternal postpartum depression: A systematic review of maternal and infant outcomes. Womens Health (Lond). 2019 Jan-Dec;15:1745506519844044. doi: 10.1177/1745506519844044.

Reference Type BACKGROUND
PMID: 31035856 (View on PubMed)

Stein A, Pearson RM, Goodman SH, Rapa E, Rahman A, McCallum M, Howard LM, Pariante CM. Effects of perinatal mental disorders on the fetus and child. Lancet. 2014 Nov 15;384(9956):1800-19. doi: 10.1016/S0140-6736(14)61277-0. Epub 2014 Nov 14.

Reference Type BACKGROUND
PMID: 25455250 (View on PubMed)

Depression and Suicide Screening Gregory Plemmons MD, MFA, in Adolescent Health Screening: an Update in the Age of Big Data, 2019

Reference Type BACKGROUND

Référentiel de psychiatrie. Collège national des universitaires en psychiatrie. Presses universitaires François Rabelais, 3ème édition, 2021

Reference Type BACKGROUND

Kroenke K, Spitzer RL, Williams JB. The Patient Health Questionnaire-2: validity of a two-item depression screener. Med Care. 2003 Nov;41(11):1284-92. doi: 10.1097/01.MLR.0000093487.78664.3C.

Reference Type BACKGROUND
PMID: 14583691 (View on PubMed)

Cox JL, Holden JM, Sagovsky R. Detection of postnatal depression. Development of the 10-item Edinburgh Postnatal Depression Scale. Br J Psychiatry. 1987 Jun;150:782-6. doi: 10.1192/bjp.150.6.782.

Reference Type BACKGROUND
PMID: 3651732 (View on PubMed)

Guedeney N, Fermanian J. Validation study of the French version of the Edinburgh Postnatal Depression Scale (EPDS): new results about use and psychometric properties. Eur Psychiatry. 1998;13(2):83-9. doi: 10.1016/S0924-9338(98)80023-0.

Reference Type BACKGROUND
PMID: 19698604 (View on PubMed)

Murray L, Carothers AD. The validation of the Edinburgh Post-natal Depression Scale on a community sample. Br J Psychiatry. 1990 Aug;157:288-90. doi: 10.1192/bjp.157.2.288.

Reference Type BACKGROUND
PMID: 2224383 (View on PubMed)

Other Identifiers

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2023-A01411-44

Identifier Type: -

Identifier Source: org_study_id

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