A Dyadic Approach to Perinatal Depression in Primary Care: Maternal Infant and Dyadic Care

NCT ID: NCT04998721

Last Updated: 2023-12-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

PHASE2

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-11-01

Study Completion Date

2025-06-01

Brief Summary

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The purpose of this study is to assess the effectiveness of a parenting intervention+usual care compared to usual care on postpartum depression and other mental health and parenting outcomes, as well as the feasibility and acceptability of the parenting intervention.

Detailed Description

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Eligible and consenting participants will be randomized in a single blind manner (research visitor will be blinded to condition) at a 1:1 ratio to either MInD (parenting intervention and usual perinatal collaborative care) or usual collaborative care in their second trimester of pregnancy. Research assessments will be administered during pregnancy and post-partum.

Conditions

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Depression, Postpartum Efficacy, Self Anxiety

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Maternal Infant Dyadic Care

Perinatal collaborative care and Promoting First Relationships-Brief

Group Type EXPERIMENTAL

Promoting First Relationships-Brief

Intervention Type BEHAVIORAL

A brief version of the evidence based Promoting First Relationships (PFR) parenting intervention in which a parent is supported in appropriate interpretation of infant cues and in developing skills to effectively parent an infant. Sessions consist of reflective content (observing and reflecting back to the mother on patterns of dyadic interaction) and informational handouts. Reflective content will be delivered in person, and text messaging protocol will deliver informational content at developmentally appropriate times. PFR-B sessions are delivered in primary care settings beginning in the third trimester and continuing postpartum.

Perinatal Collaborative Care

Intervention Type BEHAVIORAL

Collaborative Care (CC) is an integrated care model that is effective in the treatment of perinatal depression. CC provides team driven, population focused, measurement guided and evidence based care to improve access and outcomes, control costs, and increase patient satisfaction.

Control

Perinatal collaborative care only

Group Type ACTIVE_COMPARATOR

Perinatal Collaborative Care

Intervention Type BEHAVIORAL

Collaborative Care (CC) is an integrated care model that is effective in the treatment of perinatal depression. CC provides team driven, population focused, measurement guided and evidence based care to improve access and outcomes, control costs, and increase patient satisfaction.

Interventions

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Promoting First Relationships-Brief

A brief version of the evidence based Promoting First Relationships (PFR) parenting intervention in which a parent is supported in appropriate interpretation of infant cues and in developing skills to effectively parent an infant. Sessions consist of reflective content (observing and reflecting back to the mother on patterns of dyadic interaction) and informational handouts. Reflective content will be delivered in person, and text messaging protocol will deliver informational content at developmentally appropriate times. PFR-B sessions are delivered in primary care settings beginning in the third trimester and continuing postpartum.

Intervention Type BEHAVIORAL

Perinatal Collaborative Care

Collaborative Care (CC) is an integrated care model that is effective in the treatment of perinatal depression. CC provides team driven, population focused, measurement guided and evidence based care to improve access and outcomes, control costs, and increase patient satisfaction.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* English speaking pregnant women between gestational age (GA) 13 - 24 weeks
* ≥ 18 years,
* EPDS score ≥10,
* Ability to send and receive text messages (TM)

Exclusion Criteria

* Severe substance use disorder in the past 6 months (score of 4 or above on the Alcohol Use Disorders Test AUDIT-C or a score of 6 or more on the Drug Abuse Screening Test (DAST).
* Active suicidal ideation as measured by follow up to a positive answer to question 10 on the EPDS.
* Bipolar disorder (Composite International Diagnostic Interview score ≥7) or psychotic disorder (assessed by chart review);
* Multiple gestation (assessed by self-report and medical record);
* Ongoing active treatment with psychotropic medications by mental health specialist (but not a PCP or Obstetrician).
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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National Institute of Mental Health (NIMH)

NIH

Sponsor Role collaborator

University of Washington

OTHER

Sponsor Role lead

Responsible Party

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Amritha Subray Bhat

Assistant Professor, School of Medicine: Psychiatry

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Amritha S Bhat, MD, MPH

Role: PRINCIPAL_INVESTIGATOR

University of Washington

Locations

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Amritha Bhat

Seattle, Washington, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Amritha Bhat, MD

Role: CONTACT

Phone: 2065433117

Email: [email protected]

Jamie Adachi, MPH

Role: CONTACT

Email: [email protected]

Facility Contacts

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Amritha Bhat

Role: primary

Other Identifiers

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1R34MH124798-01

Identifier Type: NIH

Identifier Source: secondary_id

View Link

STUDY00011405

Identifier Type: -

Identifier Source: org_study_id