Correlation Between Epistaxis and Cardiovascular Disease

NCT ID: NCT02677467

Last Updated: 2016-02-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-03-31

Study Completion Date

2016-08-31

Brief Summary

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Investigators examine blood-pressure variance, several cardiovascular risk factors of patient with epistaxis. As a result of collected data, investigators look into correlation between epistaxis and hypertensive cardiovascular disorder.

Detailed Description

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This study is prospective observational single blinded study.

A participant is visit in the ER who patient with epistaxis.

Investigators will enroll 50 patients with epistaxis. Exclusion criteria is that patient needs immediately treatment for hypertensive urgency or patient with nasal trauma.

Investigators examine blood-pressure (BP) at five times in Emergency Department (ED) and out-patient department (opd) of Otorhinolaryngology (OL) . Investigators explain this study and ask to write consent for participant. After proper management of epistaxis, investigators get blood sampling of the participant and, the participant has a reservation to "opd of cardiovascular division of Internal Medicine" (CV opd) in the hospital.

When the participant visit CV opd, the participant undergo 24-hours-BP-monitoring and Pulse wave velocity (PWV).

After that, the participant will be follow-up for 3 months.

Investigators collect 50 data from 50 participants as a registry and analyze the data.

Conditions

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Cardiovascular Disease Epistaxis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Spontaneous epistaxis

A participant enroll if their age is over 18 with spontaneous epistaxis and their cause of visiting ER is spontaneous epistaxis. Exclusion criteria is that they needs immediately treatment for hypertensive urgency. And, they don't want to participate in this investigation. Investigators examine their blood-pressure variability and cardiovascular risk throughout their blood sample analysis.

Blood-pressure variability

Intervention Type BIOLOGICAL

Day to Night Blood pressure variability

Bleeding of wound

A participant enroll if their age is over 18 with bleeding of wound and their cause of visiting ER is to bleed on wound. Exclusion criteria is that their wounds' condition is serious or their pain is much severe. And, they don't want to participate in this investigation. Investigators examine their blood-pressure variability and cardiovascular risk throughout their blood sample analysis.

Blood-pressure variability

Intervention Type BIOLOGICAL

Day to Night Blood pressure variability

Interventions

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Blood-pressure variability

Day to Night Blood pressure variability

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* age is over 18 with spontaneous epistaxis


* age is over 18 with bleeding of wound

Exclusion Criteria

* they needs immediately treatment for hypertensive urgency.
* they don't want to participate in this investigation.

Group B


* their wounds' condition is serious or their pain is much severe.
* they don't want to participate in this investigation.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Hanyang University

OTHER

Sponsor Role lead

Responsible Party

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LEE YOON-JE

Fellowship, Emergency Medincine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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JUNGHOON SHIN, M.D., Ph.D.

Role: STUDY_CHAIR

Hanyang University

Locations

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Hanyang University Guri Hospital

Guri-si, Gyeonggi-do, South Korea

Site Status

Countries

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South Korea

Central Contacts

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YOONJE LEE, M.D.

Role: CONTACT

+82-31_560-2053

CHANGSUN KIM, M.D., Ph.D.

Role: CONTACT

+82-31-560-2057

Facility Contacts

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YOONJE LEE, M.D.

Role: primary

+82-31-560-2053

Other Identifiers

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Gurivengers

Identifier Type: -

Identifier Source: org_study_id

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