Intertrochanteric Femoral Fracture Fixation Trial

NCT ID: NCT02627040

Last Updated: 2019-11-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

95 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-11-30

Study Completion Date

2020-09-30

Brief Summary

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The main goal of the study is to determine which cephalomedullary nail results in a better functional outcome for the patient with an unstable intertrochanteric hip fracture. Subjects will be randomized to fixation with either a Gamma3 cephalomedullary nail or an InterTan cephalomedullary nail. Outcomes will be reviewed over a 12 month follow-up period.

Detailed Description

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Primary Hypotheses:

Patients who maintain their initial fracture reduction and subsequent position over time with minimal femoral neck shortening and varus will demonstrate significantly improved functional abilities, including gait and abductor function.

Secondary Objective:

* Whether radiographic differences in femoral neck shortening and varus collapse translate into a worse functional outcome to the patient.
* Whether there are differences in mortality between treatments
* Whether there is a time frame follow up after which there is no difference in outcomes.
* Evaluate the device used for fracture stabilization as a potentially contributing factor for maintenance of normal or near-normal abductor function and gait.

Primary Outcome:

The primary outcome will be functional abilities at 3, 6 and 12 months after injury. The following measures of functional ability will be utilized:

Methods:

This is a prospective, randomized non-blinded study. Patients will be identified as they present to the orthopaedic trauma service of Tampa General Hospital with a qualifying injury to determine their interest in participating in the study. Written informed consent will be obtained prior to initiation of any study procedures.

Group A will undergo cephalomedullary nail-based single screw intertrochanteric hip fracture fixation device (Gamma 3 nail). Group B will receive the integrated dual screw intertrochanteric hip fracture fixation device (Intertan nail). Patient outcomes will be analyzed using intention to treat principles. Following randomization assignment, surgeons will all follow the identical described surgical technique, with the only variable being the implant used. Post-operative immobilization and time to weight bearing and rehabilitation protocols will be again identical for all patients regardless of fixation technique.

Conditions

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Intertrochanteric Fracture Hip Fracture

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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InterTan Intertrochanteric Nail

'Surgical fixation' of intertrochanteric fracture with a cephalomedullary nail with an InterTan device (two-integrated screws)

Group Type ACTIVE_COMPARATOR

InterTan Intertrochanteric Nail

Intervention Type DEVICE

Cephalomedullary fixation of intertrochanteric fracture with an InterTan Intertrochanteric Nail

Gamma 3 Intertrochanteric Nail

'Surgical fixation' of intertrochanteric fracture with a cephalomedullary nail and Gamma 3 locking nail (single screw)

Group Type ACTIVE_COMPARATOR

Gamma 3 Intertrochanteric Nail

Intervention Type DEVICE

Cephalomedullary fixation of intertrochanteric fracture with an Gamma 3 Intertrochanteric Nail

Interventions

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InterTan Intertrochanteric Nail

Cephalomedullary fixation of intertrochanteric fracture with an InterTan Intertrochanteric Nail

Intervention Type DEVICE

Gamma 3 Intertrochanteric Nail

Cephalomedullary fixation of intertrochanteric fracture with an Gamma 3 Intertrochanteric Nail

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patients surgically treated for an intertrochanteric femur fracture at Tampa General Hospital.

* Skeletally mature patients over the age of 60; both genders.
* Community ambulators.

Exclusion Criteria

* Patients with ipsilateral lower extremity injury
* Patients under age 60
* Co-existent, severe knee or back problems
* Muscle contracture around the knee or hip joint
* Individuals who have had TKA within 6 months
* Body mass index (BMI; kg/m2) \>40
* Suspicious of pathologic fracture (tumor in origin)
* Pre-op mobility: Non ambulatory; ambulatory indoors with living support
* Cognitive impairment or dementia
* Prisoners or impending incarceration
* Homeless or no stable address.
Minimum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Florida Orthopaedic Institute

NETWORK

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Hassan R Mir, MD, MBA

Role: PRINCIPAL_INVESTIGATOR

Florida Orthopaedic Institute

Locations

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Brandon Regional Hospital

Brandon, Florida, United States

Site Status

Tampa General Hospital

Tampa, Florida, United States

Site Status

Countries

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United States

Other Identifiers

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00023144

Identifier Type: -

Identifier Source: org_study_id

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