Incidence of Cut-out Using Intramedullary Nails With Double Cephalic Screw vs. Unique in Pertrochanteric Fractures

NCT ID: NCT06293495

Last Updated: 2024-03-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-03-01

Study Completion Date

2026-04-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The goal of this clinical trial is to compare outcomes in the treatment of proximal femur fractures. The main question it aims to answer is whether the use of a double cephalic screw prevents nail failure (cut-out).

Participants will be treated using open reduction and internal fixation with a proximal femoral nail. Researchers will compare intramedullary nailing with a single cephalic screw (Gamma nail) and with a double cephalic screw (Chimaera nail) to see the cut-out rate.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Randomized, open and prospective clinical trial.

Following the surgical indication for open reduction and internal fixation as treatment for proximal femoral fractures, patients will be randomly assigned (ratio 1:1) to one of the following treatments:

Control group: a Gamma 3 nail (single cephalic screw system) will be used for osteosynthesis of the fracture.

Experimental group: a Chimaera nail (system with double cephalic screw) will be used for osteosynthesis of the fracture.

Patient (or their legal guardian) must provide/sign the informed consent prior to inclusion in the study.

After the surgery, patients will be followed-up at 6 weeks, 3 and 6 months. At those times, data related to the radiological examination, the appearance of complications and the walking ability evaluation scale (FAC) will be collected.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Proximal Femoral Fractures

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized, prospective trial with a CE-marked medical devices
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Single Cephalic Screw System

A Gamma 3 nail (single cephalic screw system) will be used for osteosynthesis of the fracture.

Group Type ACTIVE_COMPARATOR

Gamma 3 Nail (Stryker)

Intervention Type DEVICE

Open reduction an internal fixation of proximal femoral fracture with a Gamma 3 nail (single cephalic screw system)

Double Cephalic Screw System

A Chimaera nail (system with double cephalic screw) will be used for osteosynthesis of the fracture.

Group Type EXPERIMENTAL

Chimaera Nail (Orthofix)

Intervention Type DEVICE

Open reduction an internal fixation of proximal femoral fracture with a Chimaera nail (system with double cephalic screw)

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Gamma 3 Nail (Stryker)

Open reduction an internal fixation of proximal femoral fracture with a Gamma 3 nail (single cephalic screw system)

Intervention Type DEVICE

Chimaera Nail (Orthofix)

Open reduction an internal fixation of proximal femoral fracture with a Chimaera nail (system with double cephalic screw)

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients with proximal femur fracture (OTA/AO 31-A1, A2 and A3) requiring surgical treatment.
* Signing of written informed consent according to current legislation before collecting any information, either by the patient or by the legal representative or by people linked by family ties.

Exclusion Criteria

* Presence of other fractures in the ipsilateral femur that condition the surgical treatment of the pertrochanteric femur fracture.
* Subcapital fracture of the proximal femur.
* Subtrochanteric fracture of the proximal femur.
* Pathological fracture.
Minimum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Puerta de Hierro University Hospital

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Pedro-José Torrijos-Garrido

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Pedro José Torrijos Garrido, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Study Principal Investigator

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Hospital Universitario Puerta de Hierro Majadahonda

Majadahonda, Madrid, Spain

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Spain

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Pedro Jose Torrijos Garrido, MD, PhD

Role: CONTACT

+34 91 191 74 85

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

CUT-OUT

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.