Reduction of Infection in Neonatal Intensive Care Units Using the Evidence-based Practice for Improving Quality
NCT ID: NCT02600195
Last Updated: 2018-08-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
15600 participants
INTERVENTIONAL
2015-05-31
2018-04-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
HEALTH_SERVICES_RESEARCH
NONE
Study Groups
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EPIQ sites
Use Evidence-based Practice for Improving Quality (EPIQ) method to develop and implement evidence-based practice changes to reduce hospital-acquired infection
Evidence-based Practice for Improving Quality (EPIQ) method
The intervention NICUs (n = 12) will receive training in the Evidence-based Practice for Improving Quality (EPIQ) method and then develop, implement, and document evidence-based practice changes to reduce hospital-acquired infection. Compliance with practice changes and neonatal outcomes will be monitored. NICUs will receive quarterly feedback on their progress, as well as access to implementation support.
Control sites
Continue current practices
No interventions assigned to this group
Interventions
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Evidence-based Practice for Improving Quality (EPIQ) method
The intervention NICUs (n = 12) will receive training in the Evidence-based Practice for Improving Quality (EPIQ) method and then develop, implement, and document evidence-based practice changes to reduce hospital-acquired infection. Compliance with practice changes and neonatal outcomes will be monitored. NICUs will receive quarterly feedback on their progress, as well as access to implementation support.
Eligibility Criteria
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Inclusion Criteria
* Admitted to the participating NICUs within 7 days after birth
* Admitted to the participating NICUs between May 1, 2015 and April 30, 2018
Exclusion Criteria
* Infants who are moribund on admission (a decision is made to provide only palliative care)
120 Days
ALL
No
Sponsors
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China Medical Board
OTHER
Children's Hospital of Fudan University
OTHER
Responsible Party
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Principal Investigators
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Yun Cao, MD, PHD
Role: PRINCIPAL_INVESTIGATOR
Children's Hospital of Fudan University
Vibhuti Shah, MD, Msc
Role: PRINCIPAL_INVESTIGATOR
University of Toronto
Shoo K Lee, MD, PHD
Role: PRINCIPAL_INVESTIGATOR
University of Toronto
Weiping Wang, MD, PHD
Role: PRINCIPAL_INVESTIGATOR
Fudan University
Locations
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The First Affiliated Hospital of Anhui Medical University
Hefei, Anhui, China
Beijing Children's Hospital
Beijing, Beijing Municipality, China
Fujian Maternity and Child Health Care Hospital
Fuzhou, Fujian, China
Gansu Maternity and Child Health Care Hospital
Lanzhou, Gansu, China
Shenzhen Maternity and Child Health Care Hospital
Shenzhen, Guangdong, China
Guangxi Maternity and Child Health Care Hospital
Nanning, Guangxi, China
Guiyang Children's Hospital
Guiyang, Guizhou, China
Children's Hospital of Hebei Province
Shijiazhuang, Hebei, China
Zhengzhou Children's Hospital
Zhengzhou, Henan, China
Hubei Maternity and Child Health Care Hospital
Wuhan, Hubei, China
Tongji Hospital Affiliated to Tongji Medical College
Wuhan, Hubei, China
The Third Xiangya Hospital of Central South University
Changsha, Hunan, China
Nanjing Children's Hospital
Nanjing, Jiangsu, China
Nanjing Maternity and Child Health Care Hospital
Nanjing, Jiangsu, China
Suzhou Municipal Hospital
Suzhou, Jiangsu, China
Wuxi Maternity and Child Health Care Hospital
Wuxi, Jiangsu, China
Jiangxi Children's Hospital
Nanchang, Jiangxi, China
Jinan Children's Hospital
Jinan, Shandong, China
Qingdao Maternity and Child Health Care Hospital
Qingdao, Shandong, China
Shanxi Maternity and Child Health Care Hospital
Taiyuan, Shanxi, China
Shanxi Maternity and Child Health Care Hospital
Xian, Shanxi, China
The First Affiliated Hospital of Xinjiang Medical University
Ürümqi, Xinjiang, China
The Second Affiliated Hospital of Wenzhou Medical College
Wenzhou, Zhejiang, China
Shanghai First Maternity and Child Health Care Hospital
Shanghai, , China
Countries
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References
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Lee SK, Aziz K, Singhal N, Cronin CM, James A, Lee DS, Matthew D, Ohlsson A, Sankaran K, Seshia M, Synnes A, Walker R, Whyte R, Langley J, MacNab YC, Stevens B, von Dadelszen P. Improving the quality of care for infants: a cluster randomized controlled trial. CMAJ. 2009 Oct 13;181(8):469-76. doi: 10.1503/cmaj.081727. Epub 2009 Aug 10.
Zhou Q, Lee SK, Jiang SY, Chen C, Kamaluddeen M, Hu XJ, Wang CQ, Cao Y. Efficacy of an infection control program in reducing ventilator-associated pneumonia in a Chinese neonatal intensive care unit. Am J Infect Control. 2013 Nov;41(11):1059-64. doi: 10.1016/j.ajic.2013.06.007. Epub 2013 Sep 14.
Polin RA, Denson S, Brady MT; Committee on Fetus and Newborn; Committee on Infectious Diseases. Strategies for prevention of health care-associated infections in the NICU. Pediatrics. 2012 Apr;129(4):e1085-93. doi: 10.1542/peds.2012-0145. Epub 2012 Mar 26.
Fanaroff AA, Hack M, Walsh MC. The NICHD neonatal research network: changes in practice and outcomes during the first 15 years. Semin Perinatol. 2003 Aug;27(4):281-7. doi: 10.1016/s0146-0005(03)00055-7.
Horbar JD, Soll RF, Edwards WH. The Vermont Oxford Network: a community of practice. Clin Perinatol. 2010 Mar;37(1):29-47. doi: 10.1016/j.clp.2010.01.003.
Peng W, Han J, Li S, Zhang L, Yang C, Guo J, Cao Y. The Association of Human Milk Feeding With Short-Term Health Outcomes Among Chinese Very/Extremely Low Birth Weight Infants. J Hum Lact. 2022 Nov;38(4):670-677. doi: 10.1177/08903344221078237. Epub 2022 Mar 2.
Luo N, Jiang S, McNamara PJ, Li X, Guo Y, Wang Y, Han J, Deng Y, Yang Y, Lee SK, Cao Y. Cardiovascular Pharmacological Support Among Preterm Infants in Chinese Referral Center Neonatal Intensive Care Units. Front Pediatr. 2021 Apr 22;9:638540. doi: 10.3389/fped.2021.638540. eCollection 2021.
Peng W, Jiang S, Li S, Xia S, Chen S, Yang Y, Lee SK, Cao Y. Human Milk Feeding Status of Preterm Infants in Neonatal Intensive Care Units in China. J Hum Lact. 2020 May;36(2):283-290. doi: 10.1177/0890334419901265. Epub 2020 Feb 20.
Other Identifiers
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14-194
Identifier Type: -
Identifier Source: org_study_id
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