"Effect of Scaling and Root Planing on Liver Function Test (Alanine Aminotransferase and Aspartate Aminotransferase) in Systemically Healthy - Chronic Periodontitis Subjects: a Clinical Trial."

NCT ID: NCT02583841

Last Updated: 2015-10-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-02-28

Study Completion Date

2015-03-31

Brief Summary

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Aim:

To evaluate effect of non- surgical periodontal therapy on liver function in systemically healthy chronic periodontitis (CP) subjects.

Materials and methods:

The study is non surgical interventional trial, includes 50 CP subjects in the age group of 35- 60 years selected from the OPD (Out Patient Department) of department of periodontology Tatyasaheb Kore Dental College and Research center (TKDC and RC), Kolhapur. CP subjects were equally divided into test group and control group. Liver function test- aspartate aminotransferase (AST), alanine aminotransferase (ALT) were checked at baseline and at 1 month after treatment. Clinical examination includes plaque index, gingival index, sulcus bleeding index, probing depth, clinical attachment loss.

Detailed Description

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Conditions

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Chronic Periodontitis (CP) Subjects.

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Study Groups

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Scaling and Root Planing( SRP)

This was an interventional study in which scaling and root planing was done in systemically healthy patients with chronic periodontitis

Group Type ACTIVE_COMPARATOR

Scaling and root planing

Intervention Type PROCEDURE

scaling and root planing as an intervention was done in patients of the test group

Control Group

Scaling and root planing was not done , that is no intervention is carried out in the patients of this group.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Scaling and root planing

scaling and root planing as an intervention was done in patients of the test group

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. Subjects with CP (moderate and severe) as per Centers for disease control and prevention (CDC) criteria 2007.
2. Patients without any known systemic diseases

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Exclusion Criteria

1. Patients who have taken anti-inflammatory/antibiotic/antioxidant within 3 months of beginning of study.
2. Subjects who have undergone periodontal treatment within six months of inception of study.
3. Smokers, tobacco habits in any form and alcoholics.
4. Pregnant and lactating women.

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Minimum Eligible Age

35 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Tatyasaheb Kore Dental College

OTHER

Sponsor Role lead

Responsible Party

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Dr. Pradnya Rajendra Khatavkar

Post graduate student

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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TatyasahebKoreDentalC

Identifier Type: -

Identifier Source: org_study_id

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