Skin Dressings Versus Lubrication to Prevent Pressure Ulcers: A Randomized Trial

NCT ID: NCT02565745

Last Updated: 2018-03-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

TERMINATED

Clinical Phase

PHASE3

Total Enrollment

689 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-12-31

Study Completion Date

2017-12-12

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Study purpose:

To assess if - in adult patients admitted to hospital with surgical or medical conditions at high/very high risk of developing pressure ulcers (PU) according to Braden scale - using skin dressing protection versus conventional care (lubricant or moisturizer cream) may prevent the incidence of in-hospital PU

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Participants will receive, in addition to the experimental/control interventions, background skin care measures, including anti- bedsore mattresses; body position changes every two hours, and shear/friction reduction.

Trained nurses will review all participants' charts and verify any report of PU until the first ambulation, discharge or death. Patients with a verified PU are referred to the institutional wound care group.

For the purpose of outcome adjudication, study personnel will email digital pictures to 2 independent, blinded outcome assessors (experts in skin care). Skin lesions will be rated in 4-level scale (EPUAP/NPUAP). In case of disagreement, a single, independent referee will confirm the presence/absence of any potential PU.

The unit for analysis will be patients developing (first occurrence, in a time-to-event analysis) PUs in the areas covered by the interventions.

See further details on eligibility, interventions and study outcomes below

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Pressure Ulcer

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Investigators Outcome Assessors
Outcome assessors unaware of the treatment allocation will be sent photographs of the target skin areas with suspected PUs.

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Skin Dressing

Hydrocolloid dressings applied during hospitalization

Group Type EXPERIMENTAL

Skin dressing

Intervention Type COMBINATION_PRODUCT

Pre-determined skin areas at risk for PUs (3 or more, depending on the prevaliing body position, prone, supine or Sims') will be covered. Dressings will be changed every 6-7 days unless found wet/contaminated

Moisturizing cream

Use of moisturizing cream, as part of conventional skin care

Group Type ACTIVE_COMPARATOR

Moisturizing cream

Intervention Type OTHER

It will be applied twice a day to the same skin areas as the experimental group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Skin dressing

Pre-determined skin areas at risk for PUs (3 or more, depending on the prevaliing body position, prone, supine or Sims') will be covered. Dressings will be changed every 6-7 days unless found wet/contaminated

Intervention Type COMBINATION_PRODUCT

Moisturizing cream

It will be applied twice a day to the same skin areas as the experimental group

Intervention Type OTHER

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Hydrocolloid dressing Skin lubricant

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Intact skin on hospital admission
* High/very high risk of PU (Braden´s scale ≤ 20 points) will be eligible.

Exclusion Criteria

* Treating physician disagree with participation
* Need for chronic use of diapers
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Fundación Cardioinfantil Instituto de Cardiología

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Olga L Cortés, RN,MSC,PhD

Role: PRINCIPAL_INVESTIGATOR

Fundacion Cardioinfantil Instituto de Cardiología

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Fundación Cardioinfantil Instituto de Cardiología

Bogotá, Cundinamarca, Colombia

Site Status

Clinica Carlos Ardila Lulle-FOSCAL

Bucaramanga, Santander Department, Colombia

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Colombia

References

Explore related publications, articles, or registry entries linked to this study.

Bergstrom N, Braden B, Kemp M, Champagne M, Ruby E. Predicting pressure ulcer risk: a multisite study of the predictive validity of the Braden Scale. Nurs Res. 1998 Sep-Oct;47(5):261-9. doi: 10.1097/00006199-199809000-00005.

Reference Type RESULT
PMID: 9766454 (View on PubMed)

Moore ZE, Webster J. Dressings and topical agents for preventing pressure ulcers. Cochrane Database Syst Rev. 2013 Aug 18;(8):CD009362. doi: 10.1002/14651858.CD009362.pub2.

Reference Type RESULT
PMID: 23955535 (View on PubMed)

McInnes E, Jammali-Blasi A, Bell-Syer SE, Dumville JC, Cullum N. Support surfaces for pressure ulcer prevention. Cochrane Database Syst Rev. 2011 Apr 13;(4):CD001735. doi: 10.1002/14651858.CD001735.pub4.

Reference Type RESULT
PMID: 21491384 (View on PubMed)

Cortes OL, Herrera VM, Salazar LD, Rojas YA, Esparza M, Taborda A, Dennis RJ. Impact of hydrocolloid dressings in the prevention of pressure ulcers in high-risk patients: a randomized controlled trial (PENFUP). Sci Rep. 2023 Dec 7;13(1):21639. doi: 10.1038/s41598-023-47483-0.

Reference Type DERIVED
PMID: 38062132 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

277865740699

Identifier Type: OTHER_GRANT

Identifier Source: secondary_id

2222-2015

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.