Trial Comparing SOC +Skin IQ MCM vs SOC for Pressure Ulcer (PU)

NCT ID: NCT02363842

Last Updated: 2015-08-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

160 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-04-30

Study Completion Date

2016-02-29

Brief Summary

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The study is a multi-center, prospective, randomized, controlled, clinical study evaluating the effects of microclimate management using Skin IQ™ MCM coverlet placed over commercially available pressure redistribution surfaces compared to standard of care (SOC). The objective of this study is to evaluate if a commercially available pressure redistribution surface when combined with the Skin IQ™ MCM coverlet will significantly reduce pressure ulcer (PU) incidence as compared to use of a commercially available pressure redistribution surface by itself by decreasing the effects of excessive moisture and temperature at the skin and surface interface.

Detailed Description

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This prospective, randomized, controlled study is designed to capture, evaluate and compare the effects of Skin IQ™ MCM coverlet placed over commercially available pressure redistribution surfaces versus commercially available pressure redistribution surface (SOC) used by itself to manage patients at risk for tissue breakdown.

Anticipation is that 160 Subjects will need to be screened and consented to achieve the desired sample size of 136 Subjects at up to 5 centers. Individual Subject, Standard Time of Observation: Up to 60 days for incidence of PU development; beyond 60 days, only hospital discharge date and disposition will be collected. The safety endpoint is the incidence of device-related serious adverse events (SAEs).

Conditions

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Pressure Ulcer

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Skin IQ™ MCM Coverlet

Skin IQ™ MCM coverlet used over a commercially available pressure redistribution surface already in use at the participating institution to manage patients at risk for tissue breakdown

Group Type EXPERIMENTAL

Skin IQ™ MCM Coverlet

Intervention Type DEVICE

Test article is the Skin IQ™ MCM, a Class II 510k exempt product. It is an overlay coverlet indicated to be used in conjunction with a pressure redistribution surface in order to aid in the prevention and treatment of skin breakdown and pressure ulcers for patients who require microclimate management of the skin.

Pressure redistribution surface

Commercially available pressure redistribution surface already in use at participating study sites (SOC) to manage patients at risk for tissue breakdown

Group Type ACTIVE_COMPARATOR

Pressure redistribution surface

Intervention Type OTHER

Standard of Care (SOC): pressure redistribution surface already in use at the participating institution to manage patients at risk for tissue breakdown

Interventions

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Skin IQ™ MCM Coverlet

Test article is the Skin IQ™ MCM, a Class II 510k exempt product. It is an overlay coverlet indicated to be used in conjunction with a pressure redistribution surface in order to aid in the prevention and treatment of skin breakdown and pressure ulcers for patients who require microclimate management of the skin.

Intervention Type DEVICE

Pressure redistribution surface

Standard of Care (SOC): pressure redistribution surface already in use at the participating institution to manage patients at risk for tissue breakdown

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Subject 18 years or older
* Deemed at risk for tissue breakdown by clinical staff via an institutional assessment protocol such as the Braden Scale, the Waterlow Scale or the Norton Scale.
* Subject, or their legal representative, is able and willing to sign an informed consent form (ICF) and willing to undergo all study related procedures.

Exclusion Criteria

* Female Subjects who report being pregnant
* Subjects with any unstable spinal injury
* Subjects with chronic renal failure requiring dialysis at the time of enrollment
* Subjects with body mass index (BMI) \> 39 as estimated at the time of enrollment
* Use of hyperbaric oxygen therapy (HBO) ≤30 days prior to screening
* Use of external warming and/or cooling devices
* Subjects who have been enrolled in this study previously
* Subjects, who in the investigator's opinion, would have any clinically significant condition that would impair the participants' ability to comply with the study procedures
* Diagnosed chronic skin disorder
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Magellan Medical Technology Consultants, Inc.

OTHER

Sponsor Role collaborator

Arjohuntleigh

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alastair McLeod

Role: STUDY_DIRECTOR

Arjohuntleigh, Inc.

Jean DeLeon, MD

Role: PRINCIPAL_INVESTIGATOR

UTSW

Susan Jones, PhD APRNCNS

Role: PRINCIPAL_INVESTIGATOR

Integris Baptist Hospital

Rose Ralzman, RNMScCETN(c)

Role: PRINCIPAL_INVESTIGATOR

Rouge Valley Health System

David Mercer

Role: PRINCIPAL_INVESTIGATOR

UVA

Locations

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Integris Baptist Medical Center

Oklahoma City, Oklahoma, United States

Site Status RECRUITING

University of Texas- Southwestern

Dallas, Texas, United States

Site Status RECRUITING

University of Virginia

Charlottesville, Virginia, United States

Site Status RECRUITING

Rouge Valley Health

Toronto, Ontario, Canada

Site Status RECRUITING

Countries

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United States Canada

Central Contacts

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Alastair McLeod

Role: CONTACT

+44(0)1582745768

Facility Contacts

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Kristin Jones

Role: primary

Condy Dolezal

Role: primary

Sandra Burks

Role: primary

Rose Raizman

Role: primary

References

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Treatment of Pressure Ulcers: Quick Reference Guide. 2009.

Reference Type BACKGROUND

Girouard K, Harrison MB, VanDenKerkof E. The symptom of pain with pressure ulcers: a review of the literature. Ostomy Wound Manage. 2008 May;54(5):30-40, 42.

Reference Type BACKGROUND
PMID: 18493092 (View on PubMed)

Lindgren M, Unosson M, Fredrikson M, Ek AC. Immobility--a major risk factor for development of pressure ulcers among adult hospitalized patients: a prospective study. Scand J Caring Sci. 2004 Mar;18(1):57-64. doi: 10.1046/j.0283-9318.2003.00250.x.

Reference Type BACKGROUND
PMID: 15005664 (View on PubMed)

Cullum N, McInnes E, Bell-Syer SE, Legood R. Support surfaces for pressure ulcer prevention. Cochrane Database Syst Rev. 2004;(3):CD001735. doi: 10.1002/14651858.CD001735.pub2.

Reference Type BACKGROUND
PMID: 15266452 (View on PubMed)

Gray M, Bohacek L, Weir D, Zdanuk J. Moisture vs pressure: making sense out of perineal wounds. J Wound Ostomy Continence Nurs. 2007 Mar-Apr;34(2):134-42. doi: 10.1097/01.WON.0000264824.95860.9e. No abstract available.

Reference Type BACKGROUND
PMID: 17413827 (View on PubMed)

Gray M. Incontinence-related skin damage: essential knowledge. Ostomy Wound Manage. 2007 Dec;53(12):28-32.

Reference Type BACKGROUND
PMID: 18184980 (View on PubMed)

Reger SI, Ranganathan VK, Sahgal V. Support surface interface pressure, microenvironment, and the prevalence of pressure ulcers: an analysis of the literature. Ostomy Wound Manage. 2007 Oct;53(10):50-8.

Reference Type BACKGROUND
PMID: 17978415 (View on PubMed)

Zhong W, Xing MM, Pan N, Maibach HI. Textiles and human skin, microclimate, cutaneous reactions: an overview. Cutan Ocul Toxicol. 2006;25(1):23-39. doi: 10.1080/15569520500536600.

Reference Type BACKGROUND
PMID: 16702052 (View on PubMed)

Reger SI, Adams TC, Maklebust JA, Sahgal V. Validation test for climate control on air-loss supports. Arch Phys Med Rehabil. 2001 May;82(5):597-603. doi: 10.1053/apmr.2001.20837.

Reference Type BACKGROUND
PMID: 11346834 (View on PubMed)

Other Identifiers

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SIQ2014-01

Identifier Type: -

Identifier Source: org_study_id

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