Airway Resistance Measurement in Children 3 to 6 Years of Age

NCT ID: NCT02563210

Last Updated: 2019-04-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

130 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-10-19

Study Completion Date

2017-05-29

Brief Summary

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In preschool aged children, the most suitable techniques to assess airway obstruction is debit interruption technic (Rint) and plethysmographic measure of specific airway resistance (sRaw). Even if Rint is easily and routinely performed, it also includes a component of lung tissue and chest wall resistance as well as respiratory tissue viscoelasticity. sRaw seems to be better for discriminating airway obstruction. These two techniques will be compared in terms of concordance in the diagnosis of pulmonary obstruction and bronchodilator response.

Detailed Description

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Conditions

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Airway Obstruction

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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airway resistance measurement

interruption and plethysmography techniques airway resistance measurement at each routine visit

Group Type EXPERIMENTAL

airway resistance measurement

Intervention Type OTHER

assessment of airway resistance

Interventions

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airway resistance measurement

assessment of airway resistance

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Child 3 to 6 years aged

Exclusion Criteria

* Height below 90 centimeters
* Opposition to participation
Minimum Eligible Age

3 Years

Maximum Eligible Age

6 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Brest

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Marie-Agnès METGES, Pr

Role: PRINCIPAL_INVESTIGATOR

University Hospital of Brest

Locations

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CHRU de Brest

Brest, , France

Site Status

Countries

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France

References

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Mauger-Hamel P, Du Boisbaudry C, Leon K, Alavi Z, Giroux-Metges MA. Relationship between baseline and post-bronchodilator interrupter resistance and specific airway resistance in preschool children. Ann Allergy Asthma Immunol. 2020 Apr;124(4):366-372. doi: 10.1016/j.anai.2020.01.003. Epub 2020 Jan 13.

Reference Type DERIVED
PMID: 31945475 (View on PubMed)

Other Identifiers

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ARC 36 (RB 15.181)

Identifier Type: -

Identifier Source: org_study_id

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