Comparison Between spIgE and Skin Prick Test of Local and Imported Aeroallergens

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

84 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-11-30

Study Completion Date

2014-06-30

Brief Summary

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The prevalence of Allergic rhinitis(AR) and asthma was increased world wide. In 1998, ISAAC found that prevalence of AR and asthma inThailand was in moderately high group.

Tests for immediated reaction SPT and spIgE, were used for evaluated sensitization of allergen in patient. They guided the investigators for proper management as well as patient education. Clinician will use the result for choose allergen in case that might need immunotherapy.

SPT is safe and more economic for patient. Specific IgE has an advantage in patient who cannot withhold antihistamine prior SPT. In United state had a trial of result between SPT and spIgE for cockroach, cat, house dust mite and mold. It showed the correlation between two tests. In Thailand, the investigators haven't had data about it yet.

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Detailed Description

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SPT and specific IgE for allergens is necessary for allergen avoidance and specific immunotherapy. To have local allergen extracts will help the patients to easier get the appropriate management

Conditions

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Immediate Hypersensitivity

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Skin prick test with aeroallergens

Mean wheal diameters of SPT with commercial and local American coakroach, house dust mite, cat, dog and mold

Group Type EXPERIMENTAL

Skin prick test

Intervention Type PROCEDURE

skin prick test to American cockroach, dog, cat, dust mite and mold allergen extracts are performed

specific IgE measurement

Intervention Type OTHER

measure specific IgE of American cockroach, dog, cat, dust mite and mold

specific IgE measurement

specific IgE levels of commercial and local American coakroach, house dust mite, cat, dog and mold

Group Type EXPERIMENTAL

Skin prick test

Intervention Type PROCEDURE

skin prick test to American cockroach, dog, cat, dust mite and mold allergen extracts are performed

specific IgE measurement

Intervention Type OTHER

measure specific IgE of American cockroach, dog, cat, dust mite and mold

Interventions

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Skin prick test

skin prick test to American cockroach, dog, cat, dust mite and mold allergen extracts are performed

Intervention Type PROCEDURE

specific IgE measurement

measure specific IgE of American cockroach, dog, cat, dust mite and mold

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient with controlled Asthma and/or AR (mild to moderate severity) who were diagnosed in Allergy clinic and ENT clinic, Siriraj hospital
* SPT positve one of American Cockroach, House dust mite, cat, dog and mold.
* Patient were consented to trial.