Use of 2-octylcyanoacrylate With Full-thickness Skin Grafts

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-08-31

Study Completion Date

2017-05-31

Brief Summary

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The purpose of this study is to determine whether the use of 2-octylcyanoacrylate during repair of cutaneous surgery wounds with full-thickness skin grafts improves scar cosmesis compared to wound closure with sutures.

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Detailed Description

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The purpose of this study is to determine whether the use of 2-octylcyanoacrylate during repair of cutaneous surgery wounds with full-thickness skin grafts improves scar cosmesis compared to wound closure with sutures. Our aims are to compare outcomes using a split wound model, where half of the wound is treated with 2-octylcyanoacrylate and the other half is repaired with sutures, per the standard of care. Three-months post-surgery, the scar will be measured via the physician observer scar assessment scale, a validated scar instrument. Our hypothesis is that 2-octylcyanoacrylate will result in cosmetically superior wound outcomes.

Conditions

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Wound Closure Techniques

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Wound closure with 2-octylcyanoacrylate

One side of the patient's wound defect will be assigned to wound closure with 2-octylcyanoacrylate liquid bonding agent).

Group Type EXPERIMENTAL

Wound Closure with 2-octylcyanoacrylate

Intervention Type PROCEDURE

Wound Closure with 5-0 Vicryl Sutures

Intervention Type PROCEDURE

Wound closure with 5-0 vicryl sutures

One side of the patient's wound defect will be assigned to wound closure with 5-0 vicryl sutures.

Group Type ACTIVE_COMPARATOR

Wound Closure with 2-octylcyanoacrylate

Intervention Type PROCEDURE

Wound Closure with 5-0 Vicryl Sutures

Intervention Type PROCEDURE

Interventions

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Wound Closure with 2-octylcyanoacrylate

Intervention Type PROCEDURE

Wound Closure with 5-0 Vicryl Sutures

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Over 18 years of age
* Able to give informed consent themselves
* Patient scheduled for cutaneous surgical procedure with predicted closure with full-thickness skin graft
* Willing to return for follow-up visits

Exclusion Criteria

* Mentally handicapped
* Unable to understand written and oral English
* Incarceration
* Under 18 years of age
* Pregnant Women
* Patients on systemic steroid therapies
* Patients with Marfans
* Patients with allergies to 2-octylcyanoacrylate

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No