BIOCLEAN MPS (Multi-Purpose Solution) VII in Combination With Biofinity Lens: A Two Week Crossover Study

NCT ID: NCT02537730

Last Updated: 2020-08-18

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

33 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-09-30

Study Completion Date

2016-06-30

Brief Summary

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Two week, Open Label, randomized, bilateral, crossover, 1 week of daily wear in each combination (lens / disinfecting cleaning system).

Detailed Description

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To determine if patients are unreactive to the lens care solution / Biofinity combination. It is expected that there will be a total of three visits: V1 (Initial), V2 (1 week), \& V3 (2 weeks).

Conditions

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Myopia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Bioclean MPS VII / comfilcon A combination

Participants were randomized to the Bioclean MPS VII / comfilcon A combination for one week during the cross over study.

Group Type ACTIVE_COMPARATOR

Bioclean MPS VII

Intervention Type DEVICE

PHMB (Polyhexamethylene biguanide) base Disinfecting and Cleaning system

comfilcon A

Intervention Type DEVICE

contact lens

Aosept Clearcare / comfilcon A combination

Participants were randomized to the Aosept Clearcare / comfilcon A combination for one week during the cross over study.

Group Type ACTIVE_COMPARATOR

Aosept Clearcare

Intervention Type DEVICE

Hydrogen Peroxide Disinfecting and Cleaning system

comfilcon A

Intervention Type DEVICE

contact lens

Interventions

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Bioclean MPS VII

PHMB (Polyhexamethylene biguanide) base Disinfecting and Cleaning system

Intervention Type DEVICE

Aosept Clearcare

Hydrogen Peroxide Disinfecting and Cleaning system

Intervention Type DEVICE

comfilcon A

contact lens

Intervention Type DEVICE

Other Intervention Names

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Biofinity

Eligibility Criteria

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Inclusion Criteria

* Is over 18 years of age (inclusive)
* Has had a self-reported visual exam in the last two years
* Has a CL (contact lens) spherical prescription between -0.25D (Diopters) and -12.00D (inclusive)
* Has less than 1.00 D spectacle cylinder in each eye
* Is correctable to a visual acuity of 20/20 or better in both eyes
* Has clear corneas and no active ocular disease
* Has read, understood and signed the informed consent letter
* Is willing to comply with the wear schedule (at least 40hrs per week)
* Is willing to comply with the visit schedule

Exclusion Criteria

* Has never worn contact lenses before
* Currently wears rigid gas permeable contact lens
* Has a history of not achieving comfortable CL (contact lens) wear (5 days per week; \> 8 hours per day)
* Has a CL prescription outside the range of -0.25D to -12.00D
* Has a spectacle cylinder greater than -0.75D of cylinder in either eye
* Has best corrected spectacle distant vision worse than 20/20 in ether eye
* Has any systemic disease affecting ocular health
* Is using any systemic or topical medications that will affect ocular health
* Has any ocular pathology or sever insufficiency of lacrimal secretion
* Has persistent, clinically significant corneal or conjunctival staining
* Has active neovascularization or any central corneal scars
* Is aphakic
* Is pregnant or lactating
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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CooperVision, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Yuji Kodama, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Kodama Eye Clinic

Locations

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Kodama Eye Clinic

Joyo-shi, Kyoto, Japan

Site Status

Higashihara Eye Clinic

Kameoka, Kyoto, Japan

Site Status

Iwasaki Eye Clinic

Osaka, Osaka, Japan

Site Status

Countries

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Japan

Other Identifiers

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CVJ-EX-MKTG-1318

Identifier Type: -

Identifier Source: org_study_id

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