Clinical Performance of a Silicone Hydrogel Lens With Use of FID 114675A

NCT ID: NCT01240135

Last Updated: 2012-07-12

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

89 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-10-31

Study Completion Date

2011-02-28

Brief Summary

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The purpose of this study is to evaluate the clinical performance of a silicone hydrogel contact lens when used with an investigational multi-purpose disinfecting solution (MPDS).

Detailed Description

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Conditions

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Contact Lens Fit Myopia

Keywords

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Contact Lens Wear Contact Lens Solution Multi-purpose disinfecting solution Myopia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

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FID 114576A / renu fresh

FID 114675A used for contact lens care per protocol-specified instructions for 14 days, followed by a minimum 1-day washout period, after which renu fresh used for contact lens care for an additional 14 days.

Group Type OTHER

FID 114675A multi-purpose disinfecting solution (MPDS)

Intervention Type DEVICE

Daily regimen, 14 days: Thoroughly wet and rub each side of study contact lens for 10 seconds, rinse each side of the lens for 10 seconds, and soak contact lens for at least 6 hours.

renu fresh Multi-Purpose Solution (MPS)

Intervention Type DEVICE

Daily regimen, 14 days: Wet study contact lens with 3 drops and rub each side of the lens for 20 seconds, rinse each side of the lens for 5 seconds, and soak contact lens for at least 4 hours.

Galyfilcon A contact lenses (Acuvue Advance)

Intervention Type DEVICE

A fresh pair of contact lenses matching subject's pre-study lenses, including parameters, dispensed at the beginning of each period for daily wear, minimum 8 hours per day, 14 days.

renu fresh / FID 114675A

Renu fresh used for contact lens care per protocol-specified instructions for 14 days, followed by a minimum 1-day washout period, after FID 114675A used for contact lens care for an additional 14 days.

Group Type OTHER

FID 114675A multi-purpose disinfecting solution (MPDS)

Intervention Type DEVICE

Daily regimen, 14 days: Thoroughly wet and rub each side of study contact lens for 10 seconds, rinse each side of the lens for 10 seconds, and soak contact lens for at least 6 hours.

renu fresh Multi-Purpose Solution (MPS)

Intervention Type DEVICE

Daily regimen, 14 days: Wet study contact lens with 3 drops and rub each side of the lens for 20 seconds, rinse each side of the lens for 5 seconds, and soak contact lens for at least 4 hours.

Galyfilcon A contact lenses (Acuvue Advance)

Intervention Type DEVICE

A fresh pair of contact lenses matching subject's pre-study lenses, including parameters, dispensed at the beginning of each period for daily wear, minimum 8 hours per day, 14 days.

Interventions

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FID 114675A multi-purpose disinfecting solution (MPDS)

Daily regimen, 14 days: Thoroughly wet and rub each side of study contact lens for 10 seconds, rinse each side of the lens for 10 seconds, and soak contact lens for at least 6 hours.

Intervention Type DEVICE

renu fresh Multi-Purpose Solution (MPS)

Daily regimen, 14 days: Wet study contact lens with 3 drops and rub each side of the lens for 20 seconds, rinse each side of the lens for 5 seconds, and soak contact lens for at least 4 hours.

Intervention Type DEVICE

Galyfilcon A contact lenses (Acuvue Advance)

A fresh pair of contact lenses matching subject's pre-study lenses, including parameters, dispensed at the beginning of each period for daily wear, minimum 8 hours per day, 14 days.

Intervention Type DEVICE

Other Intervention Names

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Alcon Multi-Purpose Disinfecting Solution (MPDS) Bausch + Lomb renu® fresh™ Multi-Purpose Solution Acuvue® Advance®

Eligibility Criteria

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Inclusion Criteria

* 18 years of age or older.
* History of at least 5 days successful daily wear (minimum 8 hours per day) of spherical, single power Acuvue® Advance® SiH contact lenses prior to Visit 1.
* Wear contact lenses a minimum of 8 hours per day prior to Visit 1.
* Vision correctable to 20/30 (Snellen) or better in each eye at distance with study lenses at Visit 1.

Exclusion Criteria

* Need to wear contact lenses on an extended wear basis (i.e., overnight) during the study.
* Use of products other than a multi-purpose solution to care for lenses at least 7 days prior to Visit 1. Pre-study use of rewetting drops is acceptable.
* History of intolerance or known sensitivity to any component of the treatments.
* Use of over-the-counter (OTC) or prescribed topical ocular medications within 7 days prior to Visit 1.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alcon Research

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Other Identifiers

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C-10-030

Identifier Type: -

Identifier Source: org_study_id