Comparison of Two Continuous Positive Airway Pressure Systems

NCT ID: NCT02535234

Last Updated: 2021-02-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-04-30

Study Completion Date

2016-06-30

Brief Summary

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Randomised crossover trial of a novel and traditional Continuous Positive Airway Pressure (CPAP) system in Obstructive Sleep Apnoea patients.

Detailed Description

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Conditions

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Obstructive Sleep Apnoea

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Arm 1

Participants randomised to Arm 1 will receive an intervention of 7 nights with the Novel system followed by 7 nights with theTraditional system

Group Type ACTIVE_COMPARATOR

Novel System

Intervention Type DEVICE

A Novel full Continuous Positive Airway Pressure (CPAP) system - Prototype Device, Mask + Accessories

Traditional System

Intervention Type DEVICE

A Traditional full Continuous Positive Airway Pressure (CPAP) system- Released Device + Accessories, Prototype Mask

Arm 2

Participants randomised to Arm 1 will receive an intervention of 7 nights with the Traditional system followed by 7 nights with the Novel system

Group Type ACTIVE_COMPARATOR

Novel System

Intervention Type DEVICE

A Novel full Continuous Positive Airway Pressure (CPAP) system - Prototype Device, Mask + Accessories

Traditional System

Intervention Type DEVICE

A Traditional full Continuous Positive Airway Pressure (CPAP) system- Released Device + Accessories, Prototype Mask

Interventions

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Novel System

A Novel full Continuous Positive Airway Pressure (CPAP) system - Prototype Device, Mask + Accessories

Intervention Type DEVICE

Traditional System

A Traditional full Continuous Positive Airway Pressure (CPAP) system- Released Device + Accessories, Prototype Mask

Intervention Type DEVICE

Other Intervention Names

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AirSense System

Eligibility Criteria

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Inclusion Criteria

* Participant is willing to provide written informed consent
* Participant is able to read and comprehend written and spoken English
* Participant is ≥ 18 years of age
* Participant has been diagnosed with Obstructive Sleep Apnoea (OSA)
* Participants has been established on Continuous Positive Airway Pressure (CPAP) for ≥ 6 months
* Participants is currently using the same mask type/variant as the interventional mask system to be evaluated
* Participants is able to participate for the duration of the study

Exclusion Criteria

* Participant is not willing to provide written informed consent
* Participant is unable to read and comprehend written and spoken English
* Participant is \< 18 years of age
* Participant has not been diagnosed with Obstructive Sleep Apnoea (OSA)
* Participant has not been established on Continuous Positive Airway Pressure (CPAP) for ≥ 6 months
* Participant is not currently using the same mask type/variant as the interventional mask system to be evaluated
* Participant is unable to participate for the duration of the study
* Participant is pregnant
* Participant is established on bi-level support therapy
* Participant, or participants bed partner, has metallic implants in head neck or chest
* Participant has a with a pre-existing lung disease or a condition that would predispose them to pneumothorax (e.g. Chronic Obstructive Pulmonary Disease (COPD), lung cancer; fibrosis of the lungs; recent (\< 2years) case of pneumonia or lung infection, lung injury)
* Participant is unsuitable to participate in the study in the opinion of the researcher
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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ResMed

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Klaus Schindhelm

Role: PRINCIPAL_INVESTIGATOR

ResMed Limited

Holger Woehrle, MD

Role: PRINCIPAL_INVESTIGATOR

ResMed

Locations

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ResMed

Sydney, New South Wales, Australia

Site Status

Countries

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Australia

References

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Peppard PE, Young T, Barnet JH, Palta M, Hagen EW, Hla KM. Increased prevalence of sleep-disordered breathing in adults. Am J Epidemiol. 2013 May 1;177(9):1006-14. doi: 10.1093/aje/kws342. Epub 2013 Apr 14.

Reference Type RESULT
PMID: 23589584 (View on PubMed)

Young T, Palta M, Dempsey J, Skatrud J, Weber S, Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med. 1993 Apr 29;328(17):1230-5. doi: 10.1056/NEJM199304293281704.

Reference Type RESULT
PMID: 8464434 (View on PubMed)

Young T, Peppard PE, Gottlieb DJ. Epidemiology of obstructive sleep apnea: a population health perspective. Am J Respir Crit Care Med. 2002 May 1;165(9):1217-39. doi: 10.1164/rccm.2109080.

Reference Type RESULT
PMID: 11991871 (View on PubMed)

Other Identifiers

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MA011015

Identifier Type: -

Identifier Source: org_study_id

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