Trial of Proton Pump Inhibitor With Prokinetics or Placebo in Patients With Laryngopharyngeal Reflux Disease
NCT ID: NCT02533349
Last Updated: 2016-06-01
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE3
200 participants
INTERVENTIONAL
2016-05-31
2017-01-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Proton pump inhibitor + prokinetics
Patient will be prescribed proton pump inhibitor (pantoprazole, 40mg, 1T QD) with prokinetics (Motilitone, 30mg, 1T, TID) for 3months.
Motilitone
30mg, 1 tablet, 3 times a day
Pantoprazole
40mg, 1 tablet, 1time a day
Proton pump inhibitor + placebo
Patient will be prescribed proton pump inhibitor (pantoprazole, 40mg, 1T QD) with placebo (Motilitone, 30mg, 1T, TID) for 3months.
Pantoprazole
40mg, 1 tablet, 1time a day
Placebo
30mg, 1 tablet, 3 times a day
Interventions
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Motilitone
30mg, 1 tablet, 3 times a day
Pantoprazole
40mg, 1 tablet, 1time a day
Placebo
30mg, 1 tablet, 3 times a day
Eligibility Criteria
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Inclusion Criteria
* Reflux Symptom Index (RSI) \> 7 and, Reflux Finding Score (RFS) \> 13
Exclusion Criteria
* Taken steroid within 3months
* Pregnancy
* Breast feeding
20 Years
65 Years
ALL
Yes
Sponsors
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Samsung Medical Center
OTHER
Responsible Party
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Man Ki Chung
Professor
Locations
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Samsung Medical Center
Seoul, Seoul, South Korea
Countries
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Facility Contacts
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References
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Glicksman JT, Mick PT, Fung K, Carroll TL. Prokinetic agents and laryngopharyngeal reflux disease: Prokinetic agents and laryngopharyngeal reflux disease: a systematic review. Laryngoscope. 2014 Oct;124(10):2375-9. doi: 10.1002/lary.24738. Epub 2014 Jun 10.
Other Identifiers
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2015-05-007-001
Identifier Type: -
Identifier Source: org_study_id
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