The Proton Pump Inhibitor (PPI) Test for the Extraesophageal Manifestation of GERD

NCT ID: NCT00539786

Last Updated: 2014-05-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2006-03-31

Brief Summary

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PPI test;empirical trial with high-dose proton-pump inhibitors (PPIs) has been shown to be a sensitive tool for diagnosing patients with GERD. However, this diagnostic strategy has not been well established in patients with extraesophageal manifestation of GERD. In this study, we aim to see the relevance of PPI test in diagnosing GERD in patients with extraesophageal symptoms.

Detailed Description

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Conditions

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Gastroesophageal Reflux Disease

Study Design

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Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Interventions

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Proton pump inhibitor (rabeprazole)

Patients receives rabeprazole 20mg AM and 20mg PM for 14 days

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Patients with extraesophageal manifestation symptoms of GERD

Exclusion Criteria

* laryngeal, pharyngeal, liver, lung, renal, or hematological disorders
* a history of gastrointestinal surgery, and a history of connective tissue disorders.
* patients with duodenal or gastric ulcers as well as other significant lesions, such as gastric cancer, esophageal cancer, or subepithelial tumors more than 1 cm observed on the upper endoscopy
Minimum Eligible Age

20 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Samsung Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Poong-Lyul Rhee

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Poong-Lyul Rhee, MD. Ph.D

Role: PRINCIPAL_INVESTIGATOR

Samsung Medical Center, Sungkyunkwan University School of Medicine

Locations

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Samsung Medical Center, Sungkyunkwan University School of Medicine

Seoul, Gangnam-gu, South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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Tae ggon Kim

Role: CONTACT

+82-2-3410-2975

Facility Contacts

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Poong Lyul Rhee, M.D., Ph.D

Role: primary

+82-2-3410-3409

Other Identifiers

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2006-03-071

Identifier Type: -

Identifier Source: org_study_id

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