Evaluation of Use of Brain Activity Monitoring for Evaluation of Depression Treatment

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

37 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-09-30

Study Completion Date

2017-01-05

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study evaluates the use of brain activity monitoring for early identification of pharmaceutical treatment efficacy and development of depression deterioration events.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Sensor-based Characterization of Depression

NCT04370002

Unipolar Depression

RECRUITING

Gaze Contingent Feedback in Major Depressive Disorder (MDD)

NCT02945735

Depression, Unipolar Depressive Disorder Depressive Disorder, Major

COMPLETED NA

A Multicentre Clinical Study

NCT07062666

the Objective Diagnosis of Depression

NOT_YET_RECRUITING

Prediction of REsponse to Depression Interventions Using Clinical and TD-fNIRS Measurements

NCT06002100

Depression Major Depressive Disorder

ENROLLING_BY_INVITATION

Artificial Intelligence in Depression - Medication Enhancement

NCT04655924

Depression

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The study will be conducted in two arms:

In arm I, participants diagnosed with depression. In arm II, healthy participants.

Arm I - Participants that need to start or switch their pharmacological antidepressant therapy will be recruited. Their clinical status will be evaluated and their EEG characteristics will be collected.

Arm II - Clinical and EEG characteristics of Healthy volunteers will collected on a similar timetable.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Depression

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Participants diagnosed with depression.

EEG monitoring and evaluation

Group Type OTHER

EEG monitoring

Intervention Type DEVICE

EEG evaluation will be done using two off the shelf EEG devices for research and consumer use. The first one is a device called MindWave by NeuroSky ltd (http://neurosky.com) the second called EPOC by Emotiv ltd (https://emotiv.com/epoc.php).

EEG evaluation will be conducted for a total duration of 20 minutes with and without auditory stimulation. The auditory stimulation will be performed using standard headphone or earphones to reduce external noises.

Healthy participants.

EEG monitoring and evaluation

Group Type OTHER

EEG monitoring

Intervention Type DEVICE

EEG evaluation will be done using two off the shelf EEG devices for research and consumer use. The first one is a device called MindWave by NeuroSky ltd (http://neurosky.com) the second called EPOC by Emotiv ltd (https://emotiv.com/epoc.php).

EEG evaluation will be conducted for a total duration of 20 minutes with and without auditory stimulation. The auditory stimulation will be performed using standard headphone or earphones to reduce external noises.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

EEG monitoring

EEG evaluation will be done using two off the shelf EEG devices for research and consumer use. The first one is a device called MindWave by NeuroSky ltd (http://neurosky.com) the second called EPOC by Emotiv ltd (https://emotiv.com/epoc.php).

EEG evaluation will be conducted for a total duration of 20 minutes with and without auditory stimulation. The auditory stimulation will be performed using standard headphone or earphones to reduce external noises.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Participant is willing and able to give informed consent for participation in the study.
* Male or Female, aged 18 -70 years (Adult, Senior)
* Able and willing to comply with all study requirements.

* Diagnosed with depression
* Being within 2 days of receiving pharmaceutical treatment for depression for the first

time or changing dose or changing type of current pharmaceutical treatment or addition to

drug of current pharmaceutical treatment.

Brief Symptom Inventory (BSI \< 2.3).

Exclusion Criteria

The participant may not enter the study if ANY of the following apply:

* Diagnosed with Psychotic disorder.
* Diagnosed with Central Neurological disorder.
* A user of recreational or illicit drugs or has had a recent history of drug or alcohol abuse

or dependence.

* Hearing disorder and/or known ear drum impairment.
* High suicide risk as judged by the research team.

Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes