Gaze Contingent Feedback in Major Depressive Disorder (MDD)

NCT ID: NCT02945735

Last Updated: 2019-12-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-11-06

Study Completion Date

2019-01-07

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to determine whether giving gaze-contingent feedback is an effective attention modification procedure, helping in the treatment of Major Depressive Disorder (MDD)

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The study examines giving depressive participants gaze-contingent feedback as a novel attention training procedure. Half of the participants will receive contingent feedback while the other half would receive non-contingent "placebo" feedback.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Depression, Unipolar Depressive Disorder Depressive Disorder, Major

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

depression cognitive bias modification MDD major depressive disorder attention bias modification treatment

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

gaze-contingent

Attention modification: participants will receive gaze-contingent feedback according to their viewing patterns

Group Type EXPERIMENTAL

Attention Modification

Intervention Type BEHAVIORAL

Feedback according to participants' viewing patterns, in order to modify their attention.

non-gaze contingent

Participants will receive non-gaze-continent feedback unrelated to their viewing patterns

Group Type PLACEBO_COMPARATOR

Attention Modification

Intervention Type BEHAVIORAL

Feedback according to participants' viewing patterns, in order to modify their attention.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Attention Modification

Feedback according to participants' viewing patterns, in order to modify their attention.

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* A signed consent form
* Men and women between the ages of 18 and 65.
* Meeting a current diagnosis of Major Depressive Disorder (MDD) according to the DSM-IV
* MDD as the primary diagnosis: In cases of co-morbidity, MDD will be deemed as the most distressing and clinically significant condition among the co-morbid disorders
* Stable pharmaco-therapy: Participants receiving a pharmacological treatment who are taking a stable medication for at least 3 months before the beginning of the procedure.

Exclusion Criteria

* Psychotic episode in the past or the present time.
* Co-morbidity with any neurological disorder (i.e., epilepsy, brain injury).
* Another psychotherapeutic treatment during the study.
* Usage of neuroleptic medication.
* Change in medication status during the study.
* Substantial usage of drugs or alcohol in the present time.
* Poor judgment capacity (i.e., children under 18 and special populations).
* High Risk of Suicide.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Tel Aviv University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Yair Bar-Haim

Professor of Psychology and Neuroscience School of Psychological Sciences Sagol School of Neuroscience Tel Aviv University

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Yair Bar-Haim, Phd

Role: PRINCIPAL_INVESTIGATOR

Tel Aviv University

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Tel-Aviv University

Tel Aviv, , Israel

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Israel

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

TAUDEPI

Identifier Type: -

Identifier Source: org_study_id