Clinical Comparison of 27+® and 23-gauge ULTRAVIT® 7500 Cpm Vitrectomy Outcomes

NCT ID: NCT02477605

Last Updated: 2018-07-02

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

137 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-07-16

Study Completion Date

2016-08-31

Brief Summary

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The purpose of this study is to compare the treatment day change between immediate postoperative and immediate preoperative intraocular pressure (IOP) between 27-gauge and 23-gauge vitrectomy instruments.

Detailed Description

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Required follow-up for this study is 3 months post treatment.

Conditions

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Vitreoretinal Disease

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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27-gauge pak

CONSTELLATION® 27-gauge combined surgical pak used during vitrectomy surgery

Group Type EXPERIMENTAL

CONSTELLATION® 27-gauge Combined Surgical Pak

Intervention Type DEVICE

Sterile single-use supplies necessary to perform 1 vitrectomy surgery: 1 ULTRAVIT® 27-gauge 7500 cuts per minute (cpm) vitrectomy probe and a 27-gauge EDGEPLUS® Valved Entry System comprised of 3 trocar/cannulas and related accessories.

Vitrectomy surgery

Intervention Type PROCEDURE

Microincisional pars plana vitrectomy (PPV) surgery for the treatment of various vitreoretinal diseases ranging from simple to advanced cases

23-gauge pak

CONSTELLATION® 23-gauge combined surgical pak used during vitrectomy surgery

Group Type ACTIVE_COMPARATOR

CONSTELLATION® 23-gauge Combined Surgical Pak

Intervention Type DEVICE

Sterile single-use supplies necessary to perform 1 vitrectomy surgery: 1 ULTRAVIT® 23-gauge 7500 cuts per minute (cpm) vitrectomy probe and a 23-gauge EDGEPLUS® trocar/cannula set comprising of 3 trocars/cannulas and related accessories.

Vitrectomy surgery

Intervention Type PROCEDURE

Microincisional pars plana vitrectomy (PPV) surgery for the treatment of various vitreoretinal diseases ranging from simple to advanced cases

Interventions

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CONSTELLATION® 27-gauge Combined Surgical Pak

Sterile single-use supplies necessary to perform 1 vitrectomy surgery: 1 ULTRAVIT® 27-gauge 7500 cuts per minute (cpm) vitrectomy probe and a 27-gauge EDGEPLUS® Valved Entry System comprised of 3 trocar/cannulas and related accessories.

Intervention Type DEVICE

CONSTELLATION® 23-gauge Combined Surgical Pak

Sterile single-use supplies necessary to perform 1 vitrectomy surgery: 1 ULTRAVIT® 23-gauge 7500 cuts per minute (cpm) vitrectomy probe and a 23-gauge EDGEPLUS® trocar/cannula set comprising of 3 trocars/cannulas and related accessories.

Intervention Type DEVICE

Vitrectomy surgery

Microincisional pars plana vitrectomy (PPV) surgery for the treatment of various vitreoretinal diseases ranging from simple to advanced cases

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Willing and able to provide informed consent and attend all required study visits;
* Requires vitrectomy in at least one eye;

Exclusion Criteria

* Previous vitrectomy or glaucoma surgery;
* Planned treatment requires scleral buckling, combined procedures (eg, cataract surgery), silicone oil, and expansive gas other than sterile air;
* Treated with topical IOP lowering medication(s) at any time from baseline assessment to time of surgery;
* Pregnant or planning to become pregnant during the course of the trial;
Minimum Eligible Age

22 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alcon Research

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Clinical Manager, Surgical, GCRA

Role: STUDY_DIRECTOR

Alcon, A Novartis Division

Locations

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Contact Alcon Call Center for Trial Locations

Fort Worth, Texas, United States

Site Status

Countries

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United States

Other Identifiers

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VRH172-P001

Identifier Type: -

Identifier Source: org_study_id

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