The Effects of TAP Block on Postsurgical Pain After Minimally Invasive Partial Nephrectomy:

NCT ID: NCT02460640

Last Updated: 2018-02-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

96 participants

Study Classification

INTERVENTIONAL

Study Start Date

2015-05-31

Study Completion Date

2017-08-31

Brief Summary

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Single-center study in order to assess whether the tap block can make extremely beneficial in terms of reducing the acute and chronic pain as well as for use of opioids and side effects related to it in patients undergoing surgery to minimally invasive partial nephrectomy.

Detailed Description

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Conditions

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Acute Pain Chronic Pain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Tap Block

the intervention will be tap block after induction of anesthesia with ropivacaine 0,5% 15ml and continuous patient-controlled analgesia with morphine

Group Type ACTIVE_COMPARATOR

Tap block

Intervention Type PROCEDURE

intravenous patient-controlled analgesia with morphine and tap block with subcostal and posterior approach with ropivacaine 0,5% 15ml+15ml

intravenous Patient controlled analgesia

Intervention Type PROCEDURE

intravenous patient-controlled analgesia with morphine

Morphine

Intervention Type DRUG

Ropivacaine

Intervention Type DRUG

No Tap Block

the patients who not receive tap block but they will be as intervention intravenous Patient controlled analgesia

Group Type ACTIVE_COMPARATOR

intravenous Patient controlled analgesia

Intervention Type PROCEDURE

intravenous patient-controlled analgesia with morphine

Morphine

Intervention Type DRUG

Interventions

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Tap block

intravenous patient-controlled analgesia with morphine and tap block with subcostal and posterior approach with ropivacaine 0,5% 15ml+15ml

Intervention Type PROCEDURE

intravenous Patient controlled analgesia

intravenous patient-controlled analgesia with morphine

Intervention Type PROCEDURE

Morphine

Intervention Type DRUG

Ropivacaine

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* asa score I,II,II
* patients scheduled for robot assisted partial nephrectomy

Exclusion Criteria

* previous abdominal surgery
* inability to provide informed consent
* allergy to the anesthetic drugs
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Regina Elena Cancer Institute

OTHER

Sponsor Role lead

Responsible Party

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Ester Forastiere

Head of Anestesiology and Critical Care Department

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Regina Elena CI

Rome, , Italy

Site Status

Countries

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Italy

References

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Covotta M, Claroni C, Costantini M, Torregiani G, Pelagalli L, Zinilli A, Forastiere E. The Effects of Ultrasound-Guided Transversus Abdominis Plane Block on Acute and Chronic Postsurgical Pain After Robotic Partial Nephrectomy: A Prospective Randomized Clinical Trial. Pain Med. 2020 Feb 1;21(2):378-386. doi: 10.1093/pm/pnz214.

Reference Type DERIVED
PMID: 31504875 (View on PubMed)

Other Identifiers

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Tap Block

Identifier Type: -

Identifier Source: org_study_id

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