Novel Approach With Double Agent Artificial Oocyte Activation for Repeated Fertilization Failure Due to Combined Sperm and Oocyte Factor
NCT ID: NCT02418416
Last Updated: 2018-09-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
400 participants
INTERVENTIONAL
2015-05-06
2016-06-30
Brief Summary
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Detailed Description
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We Do intracytoplasmic sperm injection and immediately activate oocyte with Ca Ionophore followed by strontium chloride activation and monitoring the embryogenesis until the blastocyst formation and pregnancy outcome in multicenter assessment.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
NONE
Study Groups
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Double activation
The Oocytes in this arm will undergo double activation with Ca ionophore 5 micro mol for 20 min them Strontium chloride 10 micro mol for 60 min.
Oocyte double chemical activation
Oocyte double chemical activation
Control arm
The Oocytes will undergo Intracytoplasmic sperm injection only
No interventions assigned to this group
Interventions
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Oocyte double chemical activation
Oocyte double chemical activation
Eligibility Criteria
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Inclusion Criteria
* poor quality Oocytes
* previous failed fertilization
* previous poor embryogenesis
Exclusion Criteria
* previous successful outcome
18 Years
44 Years
FEMALE
Yes
Sponsors
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Al Baraka Fertility Hospital
OTHER
Banon IVF Center Assiut, Egypt
OTHER
Ibn Sina Hospital
OTHER_GOV
Responsible Party
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Muhammad Fawzy
IVF Laboratory Director
Locations
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Al Barka fertility center
Bahrain, , Bahrain
Banon fertility center
Asyut, , Egypt
IbnSina IVF unit, IbnSina Hospital, El Areef Square
Sohag, , Egypt
Countries
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Other Identifiers
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IbnSina Hospital IVF
Identifier Type: -
Identifier Source: org_study_id
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