Effects of Replacing Diet Beverages With Water on Weight Loss and Plasma Glucose Control in Type 2 Diabetes
NCT ID: NCT02412774
Last Updated: 2019-10-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
81 participants
INTERVENTIONAL
2015-04-30
2016-01-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Diet Beverages (DBs)
Diet beverages after the main meal+ Diet
DBs at the end of the main meal + Diet
Subjects are asked to have 250 ml DBs at the end of their lunch as the main meal, while they are on a multidisciplinary diet plan for 24 weeks.
Water
Water after the main meal+ Diet
Water at the end of the main meal+ Diet
Subjects are asked to have 250 ml water at the end of their lunch as the main meal, while they are on a multidisciplinary diet plan for 24 weeks.
Interventions
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DBs at the end of the main meal + Diet
Subjects are asked to have 250 ml DBs at the end of their lunch as the main meal, while they are on a multidisciplinary diet plan for 24 weeks.
Water at the end of the main meal+ Diet
Subjects are asked to have 250 ml water at the end of their lunch as the main meal, while they are on a multidisciplinary diet plan for 24 weeks.
Eligibility Criteria
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Inclusion Criteria
* Monotherapy with Metformin.
* 18-45 years of age.
* Body mass index (BMI) between 27-35 kg/ m².
* Consume DBs regularly during their habitual diet.
* Must be able to have moderate exercise.
* Must be interested to have weight loss.
Exclusion Criteria
* Pregnancy or lactation during the previous 6 months, or planned pregnancy in the next six months.
* Taking medication that could affect metabolism or change body weight.
* Report heart problems, chest pain, and cancer within the last five years.
* Unwilling to change intake of beverages during the study period.
18 Years
45 Years
FEMALE
No
Sponsors
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University of Nottingham
OTHER
Tehran University of Medical Sciences
OTHER
Novindiet Clinic
OTHER
Responsible Party
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Principal Investigators
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Hamid R Farshchi, MD, PhD
Role: STUDY_CHAIR
NovinDiet Clinic, School of Life Sciences, The University of Nottingham
Ameneh Madjd, Dr
Role: PRINCIPAL_INVESTIGATOR
NovinDiet Clinic, School of Life Sciences, The University of Nottingham
Ian A Macdonald, Prof.
Role: PRINCIPAL_INVESTIGATOR
School of Life Sciences, The University of Nottingham
Moira A Taylor, PhD
Role: PRINCIPAL_INVESTIGATOR
School of Life Sciences, The University of Nottingham
Reza Malekzadeh, Prof.
Role: PRINCIPAL_INVESTIGATOR
Digestive Disease Research Institute, Tehran University of Medical Sciences
Alireza Delavari, MD
Role: PRINCIPAL_INVESTIGATOR
Digestive Disease Research Institute, Tehran University of Medical Sciences
Locations
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NovinDiet Clinic
Tehran, , Iran
Countries
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References
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Lohner S, Kuellenberg de Gaudry D, Toews I, Ferenci T, Meerpohl JJ. Non-nutritive sweeteners for diabetes mellitus. Cochrane Database Syst Rev. 2020 May 25;5(5):CD012885. doi: 10.1002/14651858.CD012885.pub2.
Other Identifiers
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ND-107
Identifier Type: -
Identifier Source: org_study_id
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