Telerehabilitation for Attention and Memory in Stroke

NCT ID: NCT02405351

Last Updated: 2023-06-15

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 7 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2015-04-30
• Study Completion Date: 2019-10-30

Brief Summary

The investigators propose to develop a Telerehabilitation approach to working memory training for patients experiencing working memory deficits post stroke. The investigators have currently developed a game-like computerized working memory training program that can be accessed via the internet for research purposes. The investigators propose to refine the website to focus more on clinically based training, and to evaluate the feasibility and initial effectiveness of this approach in a pilot study with participants after stroke.

Detailed Description

Vascular disease and stroke often affect working memory, which is the ability to hold information in mind in order to deal with tasks, such as reading, having a conversation, problem-solving and decision-making. Working memory deficits can lead to problems with everyday activities, affecting independence and quality of life. Thus, interventions to improve working memory are important for optimal health outcomes in individuals after stroke.

Currently, approaches to provide interventions for working memory deficits are limited to intensive face-to-face rehabilitation sessions requiring trained therapists over many weeks. Even one-on-one computerized training requires significant health care resources, however, including supervision of daily sessions by a trained therapist, set-up of the program on the computer, teaching the patient how to use the program, regular encouragement and feedback to maintain motivation, monitoring of progress, and trouble-shooting when there are difficulties. Thus, access to these interventions is usually restricted to patients currently in hospital in urban areas, and limited or not available to those in the community once discharged, or when treated in hospital in more rural settings. Thus, new approaches to increase accessibility of this intervention approach to patients are needed.

The investigators developed one method of working memory training which uses a computerized, game-like approach, which is ideal for providing intensive, repetitive practice, with feedback and monitoring of progress. While the maximally effective dose is not yet identified, adaptive training practice normally is provided for 5 days/week for 5-10 weeks. With this intensity, computerized working memory training has been shown to improve cognitive abilities in a range of groups (e.g., healthy younger and older adults, those with Attention deficit hyperactivity disorder (ADHD), stroke, schizophrenia) and these benefits can generalize to other cognitive abilities and be maintained, at least in the short term.

The investigators propose to develop and evaluate an internet-based intervention approach, using the computerized working memory method that has been shown to be effective in improving working memory in several patient groups, including stroke. The investigators will develop and refine a website that the investigators can use to provide an already available computerized game-like software program for working memory training, and conduct an initial evaluation of this approach for feasibility and effectiveness in a pilot study involving clinical sites in Nova Scotia.

Conditions

Stroke

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: TREATMENT
• Blinding Strategy: NONE

Study Groups

Training Group

Participants will be 10 individuals post stroke, living in the community. The intervention, adaptive working memory training, is a dual n-back working memory task. This training will take place once for 30 minutes per day, 5 days a week for 6 weeks, with one week dedicated for familiarizing participants to the program in the very beginning (i.e., Week 1).

Group Type: EXPERIMENTAL

Adaptive Working Memory Training

Intervention Type: BEHAVIORAL

The working memory training task will consist of an online adaptive working memory program that will test and extend patients' working memory capacity.

Adaptive refers to the increase in the number of items that the patient is required to remember.

Interventions

Adaptive Working Memory Training

The working memory training task will consist of an online adaptive working memory program that will test and extend patients' working memory capacity.

Adaptive refers to the increase in the number of items that the patient is required to remember.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• at least 3 months post first stroke documented clinically or by imaging
• subjective concerns or objective assessment data regarding deficits in attention and working memory ability
• normal or corrected-to-normal vision
• have access to a computer at home

Exclusion Criteria

• severe aphasia or dementia
• other neurological diagnosis such as epilepsy, multiple sclerosis, Parkinson's disease
• current diagnosis of a severe psychiatric disorder such as major depressive disorder or psychosis

• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Heart and Stroke Foundation of Canada

OTHER

Sponsor Role: collaborator

Nova Scotia Health Authority

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Sarah Dolan, BSc

Role: STUDY_DIRECTOR

Dalhousie University

Gail A Eskes, PhD

Role: PRINCIPAL_INVESTIGATOR

Dalhousie University

Stephen Phillips, MD

Role: STUDY_CHAIR

Capital District Health Authority; Dalhousie University

Anita Mountain, MD

Role: STUDY_CHAIR

Capital District Health Authority; Dalhousie University

Diane MacKenzie, PhD

Role: STUDY_CHAIR

Capital District Health Authority; Dalhousie University

Mary Gorman, MD

Role: STUDY_CHAIR

St. Martha's Regional Hospital; Dalhousie University

Peggy Green

Role: STUDY_CHAIR

Nova Scotia Health Authority

Locations

Dalhousie University

Halifax, Nova Scotia, Canada

Countries

Canada

Other Identifiers

TEAMS02102014

Identifier Type: -

Identifier Source: org_study_id