CPAP Effect on Blood Pressure and Arterial Stiffness in Obstructive Sleep Apnea Patients With Resistant Hypertension
NCT ID: NCT02385864
Last Updated: 2016-03-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
UNKNOWN
166 participants
OBSERVATIONAL
2015-09-30
2017-02-28
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
The prospective observational POP-ART study will assess the efficacy of continuous positive airway pressure (CPAP) treatment on BP in patients with resistant hypertension and collect data from usual care.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Effect of Continuous Positive Airway Pressure (CPAP) on Hypertension and Cardiovascular Morbidity-Mortality in Patients With Sleep Apnea and no Daytime Sleepiness
NCT00127348
Antihypertensive Effect of Continuous Positive Airway Pressure in Resistant Hypertensive Patients With Sleep Apnea
NCT00929175
Central and Peripheral Blood Pressure in Treatment of Obstructive Sleep Apnea.
NCT02078778
Efficacy of CPAP Treatment on Blood Pressure of Resistant Hypertension Patients With Obstructive Sleep Apnea Syndrome
NCT01508754
Sleep Apnea and Refractory Hypertension: Prevalence and Effect of CPAP Treatment
NCT00459914
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
But only few studies have raised data about the effect of CPAP treatment on BP in patients with resistant hypertension.
Hypertension is moreover associated with increased arterial stiffness, but no data are available in patients with resistant hypertension.
The purpose of this study is to demonstrate that OSA has a major impact in resistant hypertension, whose effects on BP and arterial stiffness can partially be reversible with CPAP treatment.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
COHORT
PROSPECTIVE
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Patient with severe OSA (apnea-hypopnea index \> 30 or \> or equal to 15 with excessive daytime sleepiness), or with mild to moderate OSA without excessive daytime sleepiness, or without OSA.
* Ambulatory patient
Exclusion Criteria
* Other identifiable causes of hypertension
* Contraindication to CPAP treatment or patient already treated with CPAP
18 Years
75 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University Hospital, Grenoble
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Jean-Philippe Baguet, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Groupe Hospitalier Mutualiste, Grenoble
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Clinique du Tondu
Bordeaux, , France
Bordeaux University Hospital
Bordeaux, , France
Clinique des Eaux Claires, Groupe Hospitalier Mutualiste
Grenoble, , France
Grenoble University Hospital
Grenoble, , France
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
2013-A00908-37
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.