Effect of CPAP on Blood Pressure in Patients With Sleep Apnea and Refractory Hypertension

NCT ID: NCT00863135

Last Updated: 2017-02-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

68 participants

Study Classification

INTERVENTIONAL

Study Start Date

2008-12-31

Study Completion Date

2016-07-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to determine the effects of CPAP treatment on blood pressure in patients with sleep apnea syndrome (SAS) and refractory arterial hypertension (RAH).

Also, some of the mechanisms mediating SAS and RAH (systemic inflammation, oxidative stress, sympathetic hyperactivity) will be analyzed.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Obstructive Sleep Apnea Refractory Arterial Hypertension

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Continuous Positive Airway Pressure

nocturnal continuous positive airways pressure

Group Type EXPERIMENTAL

CPAP

Intervention Type DEVICE

continuous positive airways pressure

Control

Waiting list,3 months without any change in their treatment, come into the CPAP procedure after that time

Group Type OTHER

Control

Intervention Type DEVICE

Patients are 3 months without any change in their treatment, and are in the waiting list to come into the CPAP procedure after that time

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

CPAP

continuous positive airways pressure

Intervention Type DEVICE

Control

Patients are 3 months without any change in their treatment, and are in the waiting list to come into the CPAP procedure after that time

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* refractory arterial hypertension and sleep apnea with apnea-hypopnea index over 15

Exclusion Criteria

* excessive sleepiness
* professional drivers
* secondary arterial hypertension
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Carlos III Health Institute

OTHER_GOV

Sponsor Role collaborator

Corporacion Parc Tauli

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Jaume Almirall

Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Jaume Almirall, Dr

Role: PRINCIPAL_INVESTIGATOR

Corporació Parc Taulí

Juan-Carlos Martinez-Ocaña, Dr

Role: STUDY_CHAIR

Corporació Parc Tauli

Antonio Ferrer, Dr

Role: STUDY_CHAIR

Corporacio Parc Tauli

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Corporacio Parc Tauli

Sabadell, Barcelona, Spain

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Spain

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

FIS PI070219

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

CPAP in SAHS Patients With Hypertension
NCT02398032 COMPLETED PHASE4