Prognosis in the Elderly Chinese: the Northern Shanghai Study

NCT ID: NCT02368938

Last Updated: 2015-02-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

5000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-08-31

Brief Summary

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The Northern Shanghai Study is a prospective community-based study, which is aimed to investigate the prognostic factors, including conventional cardiovascular risk factors and asymptomatic target organ damage, for mortality and cardiovascular diseases, in 5,000 elderly Chinese.

Detailed Description

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Conditions

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Cardiovascular Risk Factor

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Time Perspective

PROSPECTIVE

Study Groups

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Several communities in the north of Shanghai

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. age≄65 years old(depending on identity card);
2. informed consent should be signed voluntarily;
3. the individuals are long-term residents in northern Shanghai.

Exclusion Criteria

1. is diagnosed serious heart disease (NYHA\>IV) or end stage renal disease (CKD \> 4);
2. suffered with cancer and life expectancy was less than 5 years;
3. has stroke within 3 months;
4. is not willing to participate in the clinical study;
5. suffered with other disease to quite the trial;
6. violated the protocol;
7. lost contact with laboratory staff.
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Shanghai 10th People's Hospital

OTHER

Sponsor Role lead

Responsible Party

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Ya-Wei Xu

Professor in medicine, clinical chief

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Shi J, Ye X, Yu S, Zhao Y, Xiong J, Ji H, Zhang Y. Vascular Aging, Cardiovascular-Kidney-Metabolic Syndrome, and Cardiovascular Risk: The Northern Shanghai Study. JACC Adv. 2025 Oct 16:102242. doi: 10.1016/j.jacadv.2025.102242. Online ahead of print.

Reference Type DERIVED
PMID: 41165644 (View on PubMed)

Ren Z, Yang H, Zhu W, Han J, Yu S, Zhao S, Meng W, Xu Y, Zhao Y, Zhang Y. Age and blood pressure stratified healthy vascular aging, organ damage and prognosis in the community-dwelling elderly: insights from the North Shanghai Study. Clin Hypertens. 2024 Nov 1;30(1):31. doi: 10.1186/s40885-024-00288-3.

Reference Type DERIVED
PMID: 39482774 (View on PubMed)

Zhao S, Tang J, Yu S, Maimaitiaili R, Teliewubai J, Xu C, Li J, Chi C, Xu Y, Zhang Y. Monocyte to high-density lipoprotein ratio presents a linear association with atherosclerosis and nonlinear association with arteriosclerosis in elderly Chinese population: The Northern Shanghai Study. Nutr Metab Cardiovasc Dis. 2023 Mar;33(3):577-583. doi: 10.1016/j.numecd.2022.12.002. Epub 2022 Dec 10.

Reference Type DERIVED
PMID: 36646605 (View on PubMed)

Lyu Y, Yu S, Chi C, Teliewubai J, Li J, Blacher J, Pu J, Zhang Y, Xu Y. Associations of Walking Activity With Hypertensive Mediated Organ Damage in Community-Dwelling Elderly Chinese: The Northern Shanghai Study. Front Cardiovasc Med. 2021 Oct 21;8:734766. doi: 10.3389/fcvm.2021.734766. eCollection 2021.

Reference Type DERIVED
PMID: 34746252 (View on PubMed)

Ren Z, Zhang J, Yu S, Zhao S, Tang J, Zheng Y, Meng W, Xu C, Zhang Y, Xu Y. Hypertension-Mediated Organ Damage Correlates With Serum Homocysteine Level in Community-Dwelling Elderly Chinese: The North Shanghai Study. Front Cardiovasc Med. 2021 May 10;8:662741. doi: 10.3389/fcvm.2021.662741. eCollection 2021.

Reference Type DERIVED
PMID: 34041284 (View on PubMed)

Xu C, Zhao S, Yu S, Chi C, Fan X, Ji H, Maimaitiaili R, Teliewubai J, Li X, Zhang Y, Xu Y. Association between organ damage and visceral adiposity index in community-dwelling elderly Chinese population: the Northern Shanghai Study. Aging Clin Exp Res. 2021 Aug;33(8):2291-2297. doi: 10.1007/s40520-020-01752-4. Epub 2020 Nov 21.

Reference Type DERIVED
PMID: 33219935 (View on PubMed)

Teliewubai J, Fan X, Ji H, Maimaitiaili R, Tang J, Zhao S, Yu S, Chi C, Xu Y, Zhang Y. Does healthy obesity exist in the elderly? Findings from the Northern Shanghai Study. Nutr Metab Cardiovasc Dis. 2020 May 7;30(5):749-757. doi: 10.1016/j.numecd.2020.01.010. Epub 2020 Jan 25.

Reference Type DERIVED
PMID: 32249139 (View on PubMed)

Fan X, Teliewubai J, Xiong J, Chi C, Lu Y, Zhu M, Zhang Y, Xu Y. Renal functional impairment in the elderly, the importance of fasting plasma glucose: the Northern Shanghai Study. Aging Clin Exp Res. 2021 Feb;33(2):353-360. doi: 10.1007/s40520-020-01527-x. Epub 2020 Mar 21.

Reference Type DERIVED
PMID: 32200498 (View on PubMed)

Chi C, Teliewubai J, Lu YY, Fan XM, Yu SK, Xiong J, Zhou YW, Ji HW, Zhang Y, Xu YW. Comparison of various lipid parameters in association of target organ damage: a cohort study. Lipids Health Dis. 2018 Aug 25;17(1):199. doi: 10.1186/s12944-018-0800-y.

Reference Type DERIVED
PMID: 30144803 (View on PubMed)

Teliewubai J, Bai B, Zhou Y, Lu Y, Yu S, Chi C, Li J, Blacher J, Xu Y, Zhang Y. Association of asymptomatic target organ damage with secreted frizzled related protein 5 in the elderly: the Northern Shanghai Study. Clin Interv Aging. 2018 Mar 6;13:389-395. doi: 10.2147/CIA.S155514. eCollection 2018.

Reference Type DERIVED
PMID: 29551893 (View on PubMed)

Xiong J, Yu X, Yu S, Bai B, Xu H, Ji H, Teliewubai J, Wang K, Chi C, Lu Y, Zhou Y, Fan X, Li J, Zhang Y, Xu Y. Comparison of central and peripheral hemodynamics in association with left ventricular diastolic dysfunction in the community-based elderly Chinese. J Am Soc Hypertens. 2017 Jun;11(6):366-375. doi: 10.1016/j.jash.2017.04.009. Epub 2017 Apr 27.

Reference Type DERIVED
PMID: 28528875 (View on PubMed)

Ji H, Xiong J, Yu S, Chi C, Fan X, Bai B, Zhou Y, Teliewubai J, Lu Y, Xu H, Zhang Y, Xu Y. Northern Shanghai Study: cardiovascular risk and its associated factors in the Chinese elderly-a study protocol of a prospective study design. BMJ Open. 2017 Mar 29;7(3):e013880. doi: 10.1136/bmjopen-2016-013880.

Reference Type DERIVED
PMID: 28360242 (View on PubMed)

Lu Y, Zhu M, Bai B, Chi C, Yu S, Teliewubai J, Xu H, Wang K, Xiong J, Zhou Y, Ji H, Fan X, Yu X, Li J, Blacher J, Zhang Y, Xu Y. Comparison of Carotid-Femoral and Brachial-Ankle Pulse-Wave Velocity in Association With Target Organ Damage in the Community-Dwelling Elderly Chinese: The Northern Shanghai Study. J Am Heart Assoc. 2017 Feb 20;6(2):e004168. doi: 10.1161/JAHA.116.004168.

Reference Type DERIVED
PMID: 28219916 (View on PubMed)

Other Identifiers

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NSS

Identifier Type: -

Identifier Source: org_study_id

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