A Prospective Cohort Study on Familial Hypercholesterolemia in Health Examination Population

NCT ID: NCT04958629

Last Updated: 2021-09-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

318 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-10-01

Study Completion Date

2023-12-31

Brief Summary

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To determine the prevalence and the prognosis in a corhort of patients with familial hypercholesterolemia (FH).

Detailed Description

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This study aims to achieve the following goals through prospective cohort study and statistical analysis: (1) to determine the prevalence of familial hypercholesterolemia (FH) in healthy people with hypercholesterolemia.(2) Compared with non FH population, the relative risk of atherosclerotic cardiovascular disease (ASCVD) in FH patients in China was calculated, and the risk prediction model of ASCVD in FH patients was constructed by using biochemical results, imaging data, biomarkers and other indicators.(3) To evaluate the benefits of different lipid-lowering strategies for FH patients in China.(4) To analyze the gene carriers of FH patients in China.

Conditions

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Familial Hypercholesterolemia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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non-FH Group

No interventions assigned to this group

FH Group

familial hypercholesterolemia

Intervention Type OTHER

Among the selected patients with hyperlipidemia, those who met the diagnostic criteria of FH were included in the study cohort as FH group.

Interventions

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familial hypercholesterolemia

Among the selected patients with hyperlipidemia, those who met the diagnostic criteria of FH were included in the study cohort as FH group.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1\) Patients with definite diagnosis of hyperlipidemia.

Exclusion Criteria

1. Age \< 18.
2. Do not agree to participate in this study.
3. secondary hypercholesterolemia.
4. Phytosteronemia.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Peking University Third Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Wei Gao, Doctor

Role: STUDY_CHAIR

Peking University Third Hospital

Central Contacts

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Wei Gao, Doctor

Role: CONTACT

+86 13901366179

Other Identifiers

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M2021098

Identifier Type: -

Identifier Source: org_study_id

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