The Effect of Locally Delivered Ciclosporin as an Adjunct to Healing After Treatment of Periodontal Pockets
NCT ID: NCT02366585
Last Updated: 2017-04-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
23 participants
INTERVENTIONAL
2015-03-31
2016-10-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Treatment with Ciclosporin
Treatment of two periodontal pockets with ciclosporin gel Non-treatment of two periodontal pockets in same patient as comparator
Ciclosporin
Ciclosporin gel applied to two periodontal pockets
Interventions
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Ciclosporin
Ciclosporin gel applied to two periodontal pockets
Eligibility Criteria
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Inclusion Criteria
* 2 pairs of contralateral interproximal periodontal sites with probing depths of ≥7mm in single-rooted teeth not associated with furcations or root furrows.The test sites should have a distance of at least two teeth to the control sites.
* Teeth selected should have a vital pulp as determined by thermal or electric stimulation
Exclusion Criteria
* Periodontal treatment during the last 6 months
* Antibiotic treatment 6 months prior to the start of the trial
* Antibiotic prophylaxis required for dental treatment
* Patients with acute infectious lesions in the areas of intended treatment
* Regular anti-inflammatory medication
* Known history of ciclosporin allergy
* Ongoing medication that may affect the clinical features of periodontitis
* Patients who are smokers
* Patients that are immuno-compromized or on immunosuppressive medication
* Patients who are pregnant or lactating
30 Years
ALL
No
Sponsors
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PerioC Limited
INDUSTRY
Responsible Party
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Principal Investigators
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Per Ramberg, PhD
Role: PRINCIPAL_INVESTIGATOR
Göteborg University
Locations
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The Sahlgrenska Academy, University of Gothenburg
Gothenburg, , Sweden
Countries
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Other Identifiers
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PERIOC_CTP001
Identifier Type: -
Identifier Source: org_study_id
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