Periocline as an Adjunct to Scaling and Root Planing for Adult Periodontitis
NCT ID: NCT00529555
Last Updated: 2014-05-09
Study Results
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View full resultsBasic Information
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COMPLETED
PHASE3
602 participants
INTERVENTIONAL
2006-01-31
2008-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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Scaling and root planing + SHAM TX
sham treatment
Scaling and root planing
scaling and root planing
Scaling and root planing + Vehicle
Placebo
Scaling and root planing
scaling and root planing
Scaling & root planing + Periocline Gel
Minocycline HCL 2.1%
minocycline HCl 2.1%
Minocycline HCl 2.1% gel as an adjunct to scaling and root planing. Dosing is by topical delivery into gingival pockets at baseline, 2 weeks, 4 weeks, 3 months and 6 months.
Interventions
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minocycline HCl 2.1%
Minocycline HCl 2.1% gel as an adjunct to scaling and root planing. Dosing is by topical delivery into gingival pockets at baseline, 2 weeks, 4 weeks, 3 months and 6 months.
Scaling and root planing
scaling and root planing
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* certain medical or dental conditions
* pregnancy
* allergy to active drug or related drugs
18 Years
ALL
No
Sponsors
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Sunstar Americas
INDUSTRY
Responsible Party
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Principal Investigators
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Robert Genco, DDS, PhD
Role: PRINCIPAL_INVESTIGATOR
State University of New York at Buffalo
Locations
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University of Alabama at Birmingham
Birmingham, Alabama, United States
University of California - San Francisco
San Francisco, California, United States
University of Florida
Gainsville, Florida, United States
University of Maryland - Dental School
Baltimore, Maryland, United States
Boston University Dental School
Boston, Massachusetts, United States
University of Michigan Oral Health Research Center
Ann Arbor, Michigan, United States
University of Minnesota
Minneapolis, Minnesota, United States
State University of New York at Buffalo, Dental Medicine
Buffalo, New York, United States
University of Pennsylvania Dental School
Philadelphia, Pennsylvania, United States
University of Texas Health Science Center at San Antonio
San Antonio, Texas, United States
Countries
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Other Identifiers
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SB-PER-05-001
Identifier Type: -
Identifier Source: org_study_id
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