Lumbar Disc Space Height in Young Disc Herniation and Degeneration Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

389 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-31

Study Completion Date

2014-11-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

As low back pain (LBP) imposes a heavy socioeconomic burden, early detection of pathologic intervertebral disc change in young adults holds high clinical relevance as a common structural cause of LBP. The investigators therefore assessed the feasibility of using X-ray disc space height measurements as a predictive evaluation method of lumbar disc herniation (LDH) and degeneration in LBP patients in their early 20s.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Pelvis Displacement and Gait Indicators in Patient With Lumbar Disc Herniation

NCT04230733

Lumbar Disc Herniation Gait Analysis Pelvis Abnormal

COMPLETED

MRI Analysis of Glycosaminoglycan Modifications Inside the Intervertebral Disk After Distraction and Posterior Fusion

NCT02815696

Lumbar Spine Instability

COMPLETED NA

A Questionnaire Survey Study for Exploring Outcomes for Patients With Disc Herniation

NCT05752838

Lumbar Disc Herniation

COMPLETED

Advanced MR Imaging in Patients With Painful, Degenerative Disc Disease: A Pilot Study

NCT00706459

Degenerative Disc Disease

TERMINATED

Restoration of Disc Height Reduces Chronic Low Back Pain

NCT00828880

Chronic Low Back Pain

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Intervertebral Disc Displacement Intervertebral Disc Degeneration Low Back Pain

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

The experimental group

Patients with intervertebral disc protrusion, extrusion, or migration at L4/5 randomly selected from a population pool of 665 patients with L-spine X-ray and L-spine MRIs taken within a week of the other test.

x-ray, MRI

Intervention Type RADIATION

The control group

Patients with normal or disc bulging readings at L4/5 randomly selected from a population pool of 665 patients with L-spine X-ray and L-spine MRIs taken within a week of the other test.

x-ray, MRI

Intervention Type RADIATION

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

x-ray, MRI

Intervention Type RADIATION

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Age 20-25 years
* L-spine X-ray and L-spine MRIs taken within a week of the other test
* Native Korean ethnicity

Exclusion Criteria

* Scoliosis with a Cobb's angle of ≥20°
* Significant vertebral deformity of any etiology (e.g. spondylolisthesis, fracture, spondylitis, neoplasm)
* Previous spinal surgery

Minimum Eligible Age

20 Years

Maximum Eligible Age

25 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes