Vitamin D Influence on Oocyte Donation

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

269 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-06-30

Study Completion Date

2015-01-31

Brief Summary

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Objective: To investigate the correlation between total and bioavailable serum 25-OH vitamin D, ovarian reserve and ovarian response to controlled stimulation in egg donors.

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Detailed Description

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Design: Retrospective study. Setting: University affiliated private IVF center. Intervention: Serum analysis of vitamin D, bioavailable vitamin D, antimullerian hormone (AMH), antral follicular count (AFC), reproductive outcome of oocytes recipients Main outcome measure: AMH, AFC, number of oocytes retrieved and number of mature oocytes, pregnancy and implantation rate of donated oocytes'recipients.

Conditions

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Disorder of Phosphate, Calcium and Vitamin D Metabolism Female Infertility Due to Diminished Ovarian Reserve Hormonal Requirement Reproductive Disorder

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Interventions

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vitamin D,AMH, AFC, reproductive outcome egg recipients

observational study of 269 donnors

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Caucasian race,
* between 18 and 34 years of age,
* all donors had normal menstrual cycles of 26-34 days,
* normal weight range (BMI 18- 25 Kg/m2),
* normal uterus and ovaries on transvaginal ultrasound (no signs of polycystic ovarian syndrome), and
* an antral follicle count (AFC) \>10,
* normal karyotype

Exclusion Criteria

* current or past exposure to radiation or hazardous chemical substances,
* history of drug use,
* family history of hereditary chromosomal diseases,
* sexually transmitted diseases

Minimum Eligible Age

18 Years

Maximum Eligible Age

34 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No