Effect of Phosphorus Supplementation on Body Weight

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

71 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-06-30

Study Completion Date

2014-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Phosphorus is a mineral that is naturally present in our foods and is required by our bodies for normal function. It has been found that phosphorus supplementation taken before meals has the potential to reduce meal size. However its long term effect has not been measured yet. It is well accepted that changes in body weight require about 3 months. Using body weight as the outcome, which is the ultimate outcome of weight loss approaches, would provide robust information on the role of phosphorus.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

The Role of Phosphorus in Diet Induced Thermogenesis (DIT) of Both Lean and Obese Subjects

NCT02482142

Obesity

COMPLETED NA

Effect of Food Acceptability on Appetite Hormones' Response in Normal Weight vs. Obese Male Subjects

NCT03779321

Eating Behavior

COMPLETED NA

Nutritional Support in Patients With Nutritional Risk. How we Can Improved the Prognosis and Quality of Life

NCT05299541

Malnutrition Quality of Life

TERMINATED NA

Calories Counting Using an App for Weight Loss

NCT04945291

Weight Loss

UNKNOWN NA

Daytime vs. Delayed Eating Among Obese Individuals

NCT03354169

Obesity

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

A double-blind, randomised, placebo-controlled trial of 63 adults aged 18 to 45 years with a body mass index (BMI) of 25 kg/m2 or higher and normal kidney function at the American University of Beirut. Participants were randomly assigned to the placebo or phosphorus group where daily placebo or phosphorus supplements were ingested with three main meals (breakfast, lunch, and dinner) for a period of 12 weeks. Primary outcomes were changes in anthropometric measures, blood metabolites (including lipid profile, glucose, and insulin), and subjective appetite scores.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Body Weight

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

phosphorus

phosphorus ingestion (375mg) with each main meal ( breakfast, lunch, dinner)

Group Type ACTIVE_COMPARATOR

phosphorus

Intervention Type DIETARY_SUPPLEMENT

phosphorus supplement

placebo

ingestion of placebo tablets with each meal ( breakfast, lunch, dinner)

Group Type PLACEBO_COMPARATOR

phosphorus

Intervention Type DIETARY_SUPPLEMENT

phosphorus supplement

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

phosphorus

phosphorus supplement

Intervention Type DIETARY_SUPPLEMENT

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* BMI\>25
* CR\>1mg/dl for women; Cr \>1.2 mg/dl for men
* GFR \>60ml/min/1.73m2

Exclusion Criteria

* BMI\<25
* presence of any significant medical disease,
* pregnancy or lactation,
* regular administration of drugs that affect body weight, and
* weight loss of 3% or more within 3 months of study entry.

Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes