Improvement of Facial Nerve Monitoring in Parotid Surgery by Sugammadex

NCT ID: NCT02314234

Last Updated: 2016-02-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-01-31

Study Completion Date

2015-12-31

Brief Summary

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To investigate the effectiveness of rapid reversal of rocuronium-induced neuromuscular block by sugammadex during IONM of facial nerve during parotid surgery

Detailed Description

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Intraoperative neuromonitoring (IONM) of facial nerve has been applied in identifying and preserving facial nerve during parotid surgery. In this setting, even a single dose of nondepolarizing muscle relaxant may lead to delayed and weakened electromyography (EMG) signal in facial nerve monitoring during parotid surgery. The aim of this study was to investigate the effectiveness of rapid reversal of rocuronium-induced neuromuscular block by sugammadex during IONM of facial nerve during parotid surgery

Conditions

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Injury to Nerve During Surgery

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Study Groups

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Control group

did not receive muscle relaxant during anesthesia

No interventions assigned to this group

Sugammadex group

received single dose of rocuronium for anesthesia and sugammadex at skin incision

sugammadex (Bridion)

Intervention Type DRUG

single dose of sugammadex at skin incision

Interventions

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sugammadex (Bridion)

single dose of sugammadex at skin incision

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* undergoing parotid surgery

Exclusion Criteria

* facial nerve injury, renal failure, liver cirrhosis, neuromuscular disease
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Kaohsiung Medical University Chung-Ho Memorial Hospital

OTHER

Sponsor Role lead

Responsible Party

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I-Cheng Lu

Visiting staff

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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I-Cheng Lu

Kaohsiung City, , Taiwan

Site Status

Countries

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Taiwan

Other Identifiers

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KMUH-IRB-20140248

Identifier Type: -

Identifier Source: org_study_id

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