Grading Scale of Vitreous Haze in Patients With Uveitis Using Ultrasonography

NCT ID: NCT02311192

Last Updated: 2023-08-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Clinical Phase

NA

Study Classification

INTERVENTIONAL

Study Start Date

2014-10-01

Study Completion Date

2016-09-30

Brief Summary

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This study is aimed at creation and validation of a vitreous haze scoring system using ultrasonography B-scan of the eye. Images will be obtained from patients with uveitis and quantification of inflammation will be done to create the scoring scale.

Detailed Description

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Patients with uveitis may present with Vitreous Haze (VH) resulting in obscuration of fundus details. VH is composed of cells and protein exudation and results in decrease visual acuity.The degree of VH is an important indicator of disease activity, severity and response to therapy in patients with uveitis. Color fundus images are commonly used to objectively document VH.

Conditions

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Uveitis

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Ultrasonography B-scan

Patients of uveitis who are included in the study will be imaged using ultrasound B-scan

Group Type EXPERIMENTAL

Ultrasonography B-scan

Intervention Type DEVICE

The patient's eye will be anesthetized. The ultrasound probe will then be used to obtain images by keeping the probe in light contact with the eye.

Interventions

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Ultrasonography B-scan

The patient's eye will be anesthetized. The ultrasound probe will then be used to obtain images by keeping the probe in light contact with the eye.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* • Ability to provide written informed consent and comply with study assessments for the full duration of the study

* Age 18 -90 years
* Diagnosis of uveitis

Exclusion Criteria

* • Patients with posterior segment complications including retinal detachment, choroidal detachment or hemorrhage

* Patients with any intraocular foreign body or displaced intraocular lens
* Patients with silicon oil filled eye or with gas tamponade.
* Patients with vitreous hemorrhage
* Patients with media opacity including visually significant cataract that precludes grading of VH based on fundus photography
Minimum Eligible Age

19 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Post Graduate Institute of Medical Education and Research, Chandigarh

OTHER

Sponsor Role collaborator

Luigi Sacco University Hospital

OTHER

Sponsor Role collaborator

University of Nebraska

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Quan D Nguyen, MD MSc

Role: PRINCIPAL_INVESTIGATOR

University of Nebraska

Giovanni Staurenghi, MD

Role: PRINCIPAL_INVESTIGATOR

Luigi Sacco Hospital

Ramandeep Singh, MS

Role: PRINCIPAL_INVESTIGATOR

Post Graduate Institute of Medical Education and Research, Chandigarh

Other Identifiers

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0583-14-EP

Identifier Type: -

Identifier Source: org_study_id

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