Levosimendan Administration and Outcome in Cardiac Surgery

NCT ID: NCT02275013

Last Updated: 2014-10-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

159 participants

Study Classification

OBSERVATIONAL

Study Start Date

2006-01-31

Study Completion Date

2013-12-31

Brief Summary

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To assess the effects on outcome of levosimendan with respect to timing of its administration on the postoperative course of high-risk cardiac surgery patients in a retrospective observational study.

Detailed Description

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Conditions

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Treatment of Left Heart Insufficiency in an Operative Setting of Cardiac Surgery

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Early

Levosimendan administration within first hour of post-operative ICU admission

Levosimendan

Intervention Type DRUG

Late

Levosimendan administration within 24 hours of post-operative ICU admission but after first hour

Levosimendan

Intervention Type DRUG

Interventions

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Levosimendan

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* patients undergoing cardiac surgery between 2006 and 2013
* levosimendan administration within 24 hours of postoperative ICU admission

Exclusion Criteria

* patients younger than 18
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Charite University, Berlin, Germany

OTHER

Sponsor Role lead

Responsible Party

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Michael Sander

Univ-Prof. Dr. med.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Charité University Medicine

Berlin, State of Berlin, Germany

Site Status

Countries

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Germany

References

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Treskatsch S, Balzer F, Geyer T, Spies CD, Kastrup M, Grubitzsch H, Wernecke KD, Erb JM, Braun JP, Sander M. Early levosimendan administration is associated with decreased mortality after cardiac surgery. J Crit Care. 2015 Aug;30(4):859.e1-6. doi: 10.1016/j.jcrc.2015.03.008. Epub 2015 Mar 13.

Reference Type DERIVED
PMID: 25837801 (View on PubMed)

Other Identifiers

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ea1-044-13b

Identifier Type: -

Identifier Source: org_study_id

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