Rate Control in Atrial Fibrillation

NCT ID: NCT02251509

Last Updated: 2016-06-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2016-12-31

Study Completion Date

2017-09-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This study will evaluate the efficacy of metoprolol tartrate compared to carvedilol on heart rate control in patients with atrial fibrillation and a rapid ventricular rate.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Atrial Fibrillation

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Carvedilol

carvedilol BID for 2 weeks

Group Type EXPERIMENTAL

Carvedilol

Intervention Type DRUG

Metoprolol tartrate

Metoprolol tartrate BID for 2 weeks

Group Type EXPERIMENTAL

Metoprolol tartrate

Intervention Type DRUG

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Carvedilol

Intervention Type DRUG

Metoprolol tartrate

Intervention Type DRUG

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Coreg Lopressor

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Permanent atrial fibrillation
* Baseline ventricular rate (prior to treatment) \> 110 bpm

Exclusion Criteria

* History of accessory tract re-entry tachycardia
* Ejection fraction \< 35% or history of NYHA Class III/IV stage C/D heart failure
* Acute coronary syndrome, percutaneous coronary intervention, or cardiac surgery in the past 2 months
* Child-Pugh class B or C hepatic dysfunction
* Uncontrolled hypertension
* Thyroid disease
* Intolerance to beta-blockers
* History of lung disease resulting in hospitalization in the past year
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Creighton University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Pallavi Bellamkonda, MBBS

Role: PRINCIPAL_INVESTIGATOR

Creighton University

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Creighton University

Omaha, Nebraska, United States

Site Status

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Caroline Nubel

Role: CONTACT

(402) 280-4032

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Caroline Nubel

Role: primary

402-280-4032

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

624918

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Rate Control in Atrial Fibrillation II
NCT02695992 COMPLETED PHASE4