Improving Radical Treatment Through MRI Evaluation of Pelvic Sigmoid Cancers
NCT ID: NCT02222844
Last Updated: 2024-10-17
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
244 participants
INTERVENTIONAL
2014-08-31
2031-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
DIAGNOSTIC
NONE
Study Groups
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Preoperative CT scan
CT-imaging of chest and abdomen / pelvis before surgery (standard treatment)
No interventions assigned to this group
Preoperative MRI scan
Standard treatment plus an additional MRI scan before surgery
Preoperative MRI scan
Standard preoperative CT of abdomen, chest and pelvis plus interventional preoperative MRI scan.
Observational
Observational only
No interventions assigned to this group
Interventions
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Preoperative MRI scan
Standard preoperative CT of abdomen, chest and pelvis plus interventional preoperative MRI scan.
Eligibility Criteria
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Inclusion Criteria
2. Is eligible for curative treatment
3. Has no irresectable metastatic disease
4. MRI can be reviewed by an MDT prior to surgery
5. Has no decision regarding radical treatment
6. Have provided written informed consent to participate in the study
7. Be aged 16 years or over
Exclusion Criteria
2. Have a synchronous second malignancy
3. Are contraindicated for MRI
4. Are contraindicated for or have allergy to Buscopan (e.g. glaucoma, small or large bowel obstruction, GFR\<30)
5. Have severe co-morbidities or previous medical history that prevent the application of eventual chemo/radiotherapy
16 Years
ALL
No
Sponsors
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Pelican Cancer Foundation
OTHER
Imperial College London
OTHER
Responsible Party
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Principal Investigators
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Gina Brown
Role: PRINCIPAL_INVESTIGATOR
Imperial College London
Locations
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Hinchingbrooke Hospital
Huntingdon, Cambridgeshire, United Kingdom
Leighton Hospital
Crewe, Cheshire, United Kingdom
University Hospital of North Tees
Stockton-on-Tees, County Durham, United Kingdom
Croydon University Hospital
Thornton Heath, Croydon, United Kingdom
Chesterfield Royal
Chesterfield, Derbyshire, United Kingdom
Queen Alexandra Hospital
Portsmouth, Hampshire, United Kingdom
St Mark's Hospital
Middlesex, Harrow, United Kingdom
Maidstone Hospital
Maidstone, Kent, United Kingdom
Queen Elizabeth the Queen Mother Hospital
Margate, Kent, United Kingdom
North Manchester General Hospital
Crumpsall, Manchester, United Kingdom
University Hospital of South Manchester & Manchester Royal Infirmary
Wythenshawe, Manchester, United Kingdom
Harrogate District Hospital
Harrogate, North Yorkshire, United Kingdom
Musgrove Park Hospital
Taunton, Somerset, United Kingdom
Yeovil District Hospital
Yeovil, Somerset, United Kingdom
Royal Marsden Hospital
Sutton, Surrey, United Kingdom
Salisbury District Hospital
Salisbury, Whiltshire, United Kingdom
Countries
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Central Contacts
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Facility Contacts
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David Leinhardt
Role: primary
Other Identifiers
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DOCUMAS: 23HH8201
Identifier Type: -
Identifier Source: org_study_id
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