Evaluation of Different Analysis Methods for Circulating Tumor Cells, Circulating Endothelial Cell, and Circulating Tumor DNA in Patient Followed for a Tumoral Pathology

NCT ID: NCT02220556

Last Updated: 2025-08-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

360 participants

Study Classification

INTERVENTIONAL

Study Start Date

2010-12-31

Study Completion Date

2018-06-30

Brief Summary

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Fifteen cohorts will be opened. Each cohort will explore one analysis method and/or tumoral type. Up to 50 patient can be included into each cohort.

Detailed Description

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Conditions

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Solid Tumor, Adult

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Interventions

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Blood sampling

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* 18 years old or more
* Performance status from 0 to 4
* Patient treated followed for histologically confirmed solid tumor type of any of these localization : breast, prostate, uterus, ovary, colon, lung, head and neck, melanoma.
* Informed consent form signed.

Exclusion Criteria

* Patient with history of other invasive cancer within 5 years.
* Patient treated for any non-invasive cancer
* Patient individually deprived of liberty or placed under the authority of a tutor
* Geographical condition potentially preventing compliance with the study protocol.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Institut Curie

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Jean-Yves Pierga, Prof.

Role: PRINCIPAL_INVESTIGATOR

Institut Curie

François-Clément Bidard, MD, PhD

Role: STUDY_CHAIR

Institut Curie

Locations

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Institut Curie

Paris, , France

Site Status

Institut Mutualiste Montsouris

Paris, , France

Site Status

Institut Curie

Saint-Cloud, , France

Site Status

Countries

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France

References

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Cabel L, Jeannot E, Bieche I, Vacher S, Callens C, Bazire L, Morel A, Bernard-Tessier A, Chemlali W, Schnitzler A, Lievre A, Otz J, Minsat M, Vincent-Salomon A, Pierga JY, Buecher B, Mariani P, Proudhon C, Bidard FC, Cacheux W. Prognostic Impact of Residual HPV ctDNA Detection after Chemoradiotherapy for Anal Squamous Cell Carcinoma. Clin Cancer Res. 2018 Nov 15;24(22):5767-5771. doi: 10.1158/1078-0432.CCR-18-0922. Epub 2018 Jul 27.

Reference Type BACKGROUND
PMID: 30054279 (View on PubMed)

Cabel L, Decraene C, Bieche I, Pierga JY, Bennamoun M, Fuks D, Ferraz JM, Lefevre M, Baulande S, Bernard V, Vacher S, Mariani P, Proudhon C, Bidard FC, Louvet C. Limited Sensitivity of Circulating Tumor DNA Detection by Droplet Digital PCR in Non-Metastatic Operable Gastric Cancer Patients. Cancers (Basel). 2019 Mar 21;11(3):396. doi: 10.3390/cancers11030396.

Reference Type BACKGROUND
PMID: 30901876 (View on PubMed)

Other Identifiers

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IC 2010-01

Identifier Type: -

Identifier Source: org_study_id

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