Clinical Validation of a Microfluidic Device for Isolation and Molecular Characterization of Circulating Tumor Cells
NCT ID: NCT01022723
Last Updated: 2018-09-14
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
817 participants
OBSERVATIONAL
2009-10-31
2018-12-31
Brief Summary
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Detailed Description
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* Characterize and identify these circulating tumor cells and demostrate cell viability with this capture method
* Apply this technology in clinically relevant settings and correlate to response to treatment and disease progression
* Elucidate predictive and pharmacodynamic biomarkers in the context of early phase trials of novel therapeutics
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Lung Cancer patients
Lung Cancer (particular focus on non smokers with adenocarcinoma)
No interventions assigned to this group
Patients with Nasopharyneal carcinoma
Patients with Nasopharyneal carcinoma
No interventions assigned to this group
Breast Cancer patients
Breast cancer patients
No interventions assigned to this group
Prostate Cancer patients
Prostate cancer patients
No interventions assigned to this group
Colorectal Cancer patients
Colorectal cancer patients
No interventions assigned to this group
Gastric Cancer patients
Gastric cancer patients
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
* Tumor types as specified: non smokers with lung adenocarcinoma, undifferentiated EBV-ISH positive nasopharyneal carcinoma, breast cancer, colorectal cancer, prostate cancer, gastric cancer
* Informed consent given for the purposes of blood sampling for this study
* Measurable disease by RECIST criteria of at least 1cm is preferred but not a sine qua non for study accrual
Exclusion Criteria
ALL
No
Sponsors
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National Medical Research Council (NMRC), Singapore
OTHER_GOV
National University of Singapore
OTHER
National Cancer Centre, Singapore
OTHER
Responsible Party
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Principal Investigators
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Wan-Teck Lim, MD
Role: PRINCIPAL_INVESTIGATOR
National Cancer Centre, Singapore
Locations
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National Cancer Centre
Singapore, , Singapore
Countries
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Central Contacts
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Other Identifiers
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CTC_ver2_081109
Identifier Type: -
Identifier Source: org_study_id
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