Identification of Marker of Primary or Acquired Resistance to Anti Tumorous Treatment

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

2200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-07-31

Study Completion Date

2019-07-31

Brief Summary

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Lung Cancer and melanoma relapsed frequently whereas its very sensitive to treatment such as chemotherapy or radiotherapy. The purpose of this study is to have a better understanding of why those patients are relapsing using next generation sequencing to identify rare mutations and assessed their predictive value.

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Detailed Description

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Conditions

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Melanoma Non Small Cell Lung Cancer Small Cell Lung Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SCREENING

Blinding Strategy

NONE

Study Groups

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Experimental arm

Blood sample Tumorous biopsy Healthy material sample

Group Type EXPERIMENTAL

Blood sample

Intervention Type PROCEDURE

Optional

Tumorous biopsy

Intervention Type PROCEDURE

Optional

Healthy material sample

Intervention Type PROCEDURE

Optional

Interventions

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Blood sample

Optional

Intervention Type PROCEDURE

Tumorous biopsy

Optional

Intervention Type PROCEDURE

Healthy material sample

Optional

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. Cytological or histological diagnosis of SCLC, NSCLC or melanoma
2. Patients age \>/= 18 years old
3. Indication of treatment using platinum salts for lung cancer except for patient with NSCLC treated by surgery for whom platinum salts is not indicated
4. If a biopsy is proposed, lesion lust be easily accessible
5. Signed informed consent