Registro Campania Salute Network on Hypertension

NCT ID: NCT02211365

Last Updated: 2025-08-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

10000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-02-28

Study Completion Date

2030-04-30

Brief Summary

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The Registro Campania Salute Network (RCSN) is a prospective registry aimed at improving the management of essential hypertension by integrating the activity of general practitioners (GPs) with that of the hypertension specialist. It involves selected GPs homogeneously allocated in the regional area, and the Hypertension Clinic of the Federico II University in Naples, which served as co-ordinating centre. Through the RCSN system it is possible to store clinical data detected at each visit between the peripheral units and the co-ordinating centre and to support scientific analysis of the dataset.

Detailed Description

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The patients will be followed over a period of twenty years and all clinical data will be recorded in order to investigate the role of hypertension and correlated disease on this patient population

Conditions

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Hypertension; Heart Disease, Hypertensive

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

-Hypertension

* 18 years old

Exclusion Criteria

* Refused to sign informed consent
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Federico II University

OTHER

Sponsor Role lead

Responsible Party

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RAFFAELE IZZO

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Bruno Trimarco, MD

Role: PRINCIPAL_INVESTIGATOR

Dipartimento di Scienze Biomediche Avanzate, Università degli Studi di Napoli Federico II

Locations

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Department od advanced biomedical sciences, Università degli studi di Napoli Federico II, Via sergio Pansini 5

Napoli, Napoli, Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Bruno Trimarco, MD

Role: CONTACT

+390817462250

eugenio stabile, MD

Role: CONTACT

+393316776019

Facility Contacts

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Raffaele Izzo, MD

Role: primary

+390817462211

eugenio Stabile, MD

Role: backup

+393316776019

References

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Mancusi C, Basile C, Gerdts E, Fucile I, Manzi MV, Lembo M, Pacella D, Giugliano G, Canciello G, Piccolo R, Spinelli A, Morisco C, De Luca N, Trimarco B, de Simone G, Bossone E, Izzo R, Losi MA, Esposito G. Carotid plaque offsets sex-related differences in cardiovascular risk of young hypertensive patients. Eur J Intern Med. 2024 Dec;130:137-143. doi: 10.1016/j.ejim.2024.09.007. Epub 2024 Sep 17.

Reference Type DERIVED
PMID: 39294033 (View on PubMed)

Trimarco V, Manzi MV, Izzo R, Mone P, Lembo M, Pacella D, Esposito G, Falco A, Morisco C, Gallo P, Santulli G, Trimarco B. The therapeutic concordance approach reduces adverse drug reactions in patients with resistant hypertension. Front Cardiovasc Med. 2023 May 5;10:1137706. doi: 10.3389/fcvm.2023.1137706. eCollection 2023.

Reference Type DERIVED
PMID: 37215551 (View on PubMed)

Lembo M, Acampa W, Rao MAE, Manzi MV, Morisco C, Esposito G, Assante R, Zampella E, Nappi C, Gaudieri V, Mannarino T, Mancusi C, de Simone G, Izzo R, Cuocolo A, Trimarco B. Left Ventricular Mechano-Energetic Efficiency Identifies an Early Impairment of Myocardial Blood Flow in Arterial Hypertension. Hypertension. 2023 Jul;80(7):1534-1543. doi: 10.1161/HYPERTENSIONAHA.123.21071. Epub 2023 May 12.

Reference Type DERIVED
PMID: 37170833 (View on PubMed)

Stabile E, Franzese M, Chianese S, Alfani A, Gerardi D, Colaiori I, Annunziata M, Nappi P, Scalise M, Di Serafino L, Puzone B, Avvedimento M, Leone A, Ilardi F, Piccolo R, Franzone A, Cirillo P, Morisco C, Trimarco B, Esposito G. Predictors of adherence to composite therapy after acute coronary syndromes. J Cardiovasc Med (Hagerstown). 2021 Aug 1;22(8):645-651. doi: 10.2459/JCM.0000000000001201.

Reference Type DERIVED
PMID: 33966020 (View on PubMed)

Mancusi C, Losi MA, Albano G, De Stefano G, Morisco C, Barbato E, Trimarco B, De Luca N, de Simone G, Izzo R. Characteristics and Outcomes of Patients Presenting With Hypertensive Urgency in the Office Setting: The Campania Salute Network. Am J Hypertens. 2020 Apr 29;33(5):414-421. doi: 10.1093/ajh/hpaa003.

Reference Type DERIVED
PMID: 31930302 (View on PubMed)

Canciello G, Mancusi C, Losi MA, Izzo R, Trimarco B, de Simone G, De Luca N. Aortic Root Dilatation Is Associated With Incident Cardiovascular Events in a Population of Treated Hypertensive Patients: The Campania Salute Network. Am J Hypertens. 2018 Nov 13;31(12):1317-1323. doi: 10.1093/ajh/hpy113.

Reference Type DERIVED
PMID: 30099532 (View on PubMed)

Mancusi C, Izzo R, Ferrara LA, Rozza F, Losi MA, Canciello G, Pepe M, de Luca N, Trimarco B, de Simone G. Is increased uric acid a risk factor or a defensive response? The Campania Salute Network. Nutr Metab Cardiovasc Dis. 2018 Aug;28(8):839-846. doi: 10.1016/j.numecd.2018.04.013. Epub 2018 May 4.

Reference Type DERIVED
PMID: 29898822 (View on PubMed)

Izzo R, Losi MA, Stabile E, Lonnebakken MT, Canciello G, Esposito G, Barbato E, De Luca N, Trimarco B, de Simone G. Development of Left Ventricular Hypertrophy in Treated Hypertensive Outpatients: The Campania Salute Network. Hypertension. 2017 Jan;69(1):136-142. doi: 10.1161/HYPERTENSIONAHA.116.08158. Epub 2016 Nov 28.

Reference Type DERIVED
PMID: 27895192 (View on PubMed)

Other Identifiers

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16/14

Identifier Type: -

Identifier Source: org_study_id

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