Research of the Application of Triple Antibiotic Paste in Primary Teeth With Pericpical Periodontitis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-06-30

Study Completion Date

2015-06-30

Brief Summary

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The triple antibiotic paste is widely used in young permanent teeth and permanent teeth root canal therapy with excellent antiantimicrobial effect.We hypothesize that its application in the treatment of periapical periodontitis of deciduous teeth is superior to other drugs currently in use as creosote.

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Detailed Description

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We design to collect a group of patients presenting primary teeth with periapical periodontitis in certain criterion. We will divide the patients into two groups randomly.One group will get treated with triple antibiotic paste while the other with creosote.We want to evaluate the short-term and long-term effects of the two groups to get a conclusion of the clinical value of triple antibiotic paste.

Conditions

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Periapical Diseases

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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creosote

Creosote ，once，three weeks Triple Antibiotic Paste ，none

Group Type ACTIVE_COMPARATOR

creosote

Intervention Type DRUG

Pulp removal,Root canal irrigation and disinfection

Triple Antibiotic Paste

Triple Antibiotic Paste,once,three weeks creosote,none

Group Type EXPERIMENTAL

Metronidazole-Ciprofloxacin gatifloxacin-Clindamycin paste

Intervention Type DRUG

Pulp removal,Root canal irrigation and disinfection,

Interventions

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Metronidazole-Ciprofloxacin gatifloxacin-Clindamycin paste

Pulp removal,Root canal irrigation and disinfection,

Intervention Type DRUG

creosote

Pulp removal,Root canal irrigation and disinfection

Intervention Type DRUG

Other Intervention Names

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oily liquid obtained by distillation of wood tar

Eligibility Criteria

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Inclusion Criteria

* clinical diagnosis of periapical periodontitis
* must be primary teeth
* must be 3\~8 years old
* the permanent tooth germ is complete and didnot be involved