REV 002 Observational Study of the ReVENT Sleep Apnea System: Minimally Invasive Treatment for Obstructive Sleep Apnea

NCT ID: NCT02180815

Last Updated: 2017-04-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2014-09-30

Study Completion Date

2017-04-30

Brief Summary

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The purpose of this post-market observational study is to assess the effectiveness and patient perception of benefit of the ReVENT Sleep Apnea System in patients diagnosed with Obstructive Sleep Apnea due to primary tongue base closure. The ReVENT Sleep Apnea System is a minimally invasive surgical approach to treat Obstructive Sleep Apnea. The ReVENT Sleep Apnea System consists of an implanter kit and tongue implants. The implants are permanently implanted in the tongue during a minimally invasive outpatient surgical procedure to prevent tongue base closure during sleep.

Detailed Description

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Conditions

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Obstructive Sleep Apnea

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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ReVENT implanted group

ReVENT Sleep Apnea System

Intervention Type DEVICE

Interventions

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ReVENT Sleep Apnea System

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Patient diagnosed with Obstructive Sleep Apnea due to primary tongue base closure.
* AHI ≥ 10 and AHI ≤ 40 (at least 90% of apneas and hypopneas must be obstructive).
* BMI ≤ 32.
* Confirmation of tongue base closure as the primary source of obstruction with Drug Induced Sleep Endoscopy (DISE).

Exclusion Criteria

* Patient with prior tongue-base surgery
* Uvulopalatopharyngoplasty, soft palate surgery, tonsillectomy or minimally invasive RF ablation of the tongue within the last six (6) months.
* History of mandibular and/or hyoid advancement to treat OSA.
* Any contraindications as listed in the approved Instructions for Use.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Revent Medical, Inc.

INDUSTRY

Sponsor Role collaborator

Revent Medical International B.V.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Prof. Dr. Wolfgang Bergler

Role: PRINCIPAL_INVESTIGATOR

St. Joseph-Stift

Locations

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Cliniques Universitaires Saint Luc

Brussels, , Belgium

Site Status

University Hospital Antwerp

Edegem, , Belgium

Site Status

Pavelec LENTE, Ltd.

Pilsen, , Czechia

Site Status

St Joseph-Stift

Bremen, , Germany

Site Status

St. Franziskus Hospital HNO-Klinik

Cologne, , Germany

Site Status

Alfried Krupp Krankenhaus

Essen, , Germany

Site Status

Asklepios Klinik Harburg

Hamburg, , Germany

Site Status

Universitäts-HNO-Klinik Mannheim

Mannheim, , Germany

Site Status

Klinikum Ernst von Bergmann

Potsdam, , Germany

Site Status

Universitätsklinikum HNO-Klinik

Ulm, , Germany

Site Status

MC Slotervaart

Amsterdam, , Netherlands

Site Status

Sint Antonius Hospital

Nieuwegein, , Netherlands

Site Status

ISALA Afdeling KNO-Heelkunde Isala

Zwolle, , Netherlands

Site Status

Cantonal Hospital Baselland - ENT Department

Liestal, , Switzerland

Site Status

Countries

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Belgium Czechia Germany Netherlands Switzerland

Other Identifiers

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REV 002

Identifier Type: -

Identifier Source: org_study_id

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