A Trial to Evaluate a Device for the Treatment of OSA and Snoring

NCT ID: NCT01772017

Last Updated: 2015-11-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

15 participants

Study Classification

INTERVENTIONAL

Study Start Date

2012-10-31

Study Completion Date

2013-08-31

Brief Summary

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To evaluate the safety and efficacy of the Tongue Advancement Retainer Device in treating subjects with Obstructive Sleep Apnea (OSA) and snoring.

Detailed Description

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The Tongue Advancement Retainer Device is a device that was developed to treat subjects with OSA and snoring. The purpose of this study is to evaluate initial safety and effectiveness of this device in treating one or both conditions.

Conditions

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Obstructive Sleep Apnea Snoring

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Device Treatment

Tongue Advancement Retainer Device

Group Type EXPERIMENTAL

Tongue Advancement Retainer Device

Intervention Type DEVICE

Tongue Advancement Retainer Device

Interventions

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Tongue Advancement Retainer Device

Tongue Advancement Retainer Device

Intervention Type DEVICE

Other Intervention Names

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Sleepy Tongue Advancement Retainer Device

Eligibility Criteria

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Inclusion Criteria

* • Aged 18-65

* AHI greater than or equal to 10 but less than or equal to 60 (\<10 AHI \<60/hr)
* Complete set of lower anterior incisors with no evidence of periodontal disease or mobility and the ability to floss between teeth

Additionally subjects will in the screening phase must:

* Tolerate the device when being fitted
* Used the device for \>4 hours on at least two consecutive nights during the screening period.
* Be able to reliably demonstrate proper installation of the device after fitting.
* Be willing to trial the device for a 4 week period

Exclusion Criteria

* • Central sleep apnea events \>10% of the total events

* Evidence of Cheyne stokes breathing
* Currently on treatment for OSA or OSA treatment discontinued less than 3 months prior.
* Currently on regular treatment with prescription hypnosedatives or prescription stimulants
* Very severe OSA, defined as AHI\>60/hour and/or minimum oxygen saturation \<75%
* Need for immediate initiation of treatment as assessed by physician (e.g. Excessive sleepiness posing driving risk)
* Previous surgery to treat OSA (other than nasal surgery)
* Evidence of periodontal disease or tooth mobility
* Severe nasal obstruction or enlarged tonsils based on clinical assessment
* Unstable cardiovascular disease (untreated hypertension acceptable).
* Inability to tolerate oral device due to oral condition or claustrophobia as determined by the study investigator
* Pregnant/Breast Feeding
* Any known factor or disease that might interfere with treatment compliance, study conduct or interpretation of the results such as co-existent other sleep disorder, psychiatric disease, history of non compliance to medical regimens, or unwillingness to comply with study requirements.
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sleepy, Inc

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Brian Weeks, MD

Role: PRINCIPAL_INVESTIGATOR

Senta Clinic

Locations

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Senta Clinic

San Diego, California, United States

Site Status

Visalia Medical Clinic

Visalia, California, United States

Site Status

Royal North Shore Hospital

St Leonards, New South Wales, Australia

Site Status

Countries

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United States Australia

Other Identifiers

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OPEN-002

Identifier Type: -

Identifier Source: org_study_id