Pre-dinner vs. Post-dinner Exercise on Glycemic Control

NCT ID: NCT02180620

Last Updated: 2017-06-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

13 participants

Study Classification

INTERVENTIONAL

Study Start Date

2013-09-30

Study Completion Date

2014-04-30

Brief Summary

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With many medications we prescribe them relative to time of day or a meal. This study established if pre dinner vs post dinner exercise was more effective at altering post dinner glucose and triglyceride levels vs no exercise at all.

Detailed Description

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All participants completed three trials in a random order in which they consumed a standardized dinner meal with 1) no RE (NoRE), 2) pre-dinner RE (RE→M), and 3) post-dinner RE beginning 45 min after dinner (M→RE). Diet was standardized during the day of testing. Participants reported to the lab for testing sometime between 3 - 5:30 p.m. and upon arrival a venous catheter was inserted into a forearm vein. Frequent blood sampling, indirect calorimetry measurements, and subjective well-being measurements ensued for \~5.75 h while the participants were in the lab.

Conditions

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Type 2 Diabetes

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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No exercise

participants will remain sedentary during testing

Group Type EXPERIMENTAL

No exercise

Intervention Type OTHER

During the no exercise trial (NoEX), the participants will remain sedentary during testing.

Meal then exercise

45 min of resistance training will be performed after a standard meal

Group Type EXPERIMENTAL

Meal then exercise

Intervention Type OTHER

During the post-meal exercise trial (M→EX), 45 min of resistance training will be performed

exercise then meal

45 min of resistance training will be performed prior to a standard meal

Group Type EXPERIMENTAL

exercise then meal

Intervention Type OTHER

During the exercise prior to the meal trial (EX→M), 45 min of resistance training will be performed

Interventions

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No exercise

During the no exercise trial (NoEX), the participants will remain sedentary during testing.

Intervention Type OTHER

Meal then exercise

During the post-meal exercise trial (M→EX), 45 min of resistance training will be performed

Intervention Type OTHER

exercise then meal

During the exercise prior to the meal trial (EX→M), 45 min of resistance training will be performed

Intervention Type OTHER

Other Intervention Names

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NoEX M-EX EX-M

Eligibility Criteria

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Inclusion Criteria

* Obese ( body mass index 30-45 kg/m2)
* Physician diagnosed with type 2 diabetes receiving standard medical care
* Non-smokers
* Pregnancy
* Lactating mothers

Exclusion Criteria

* Insulin
* Surgical weight loss
* Orthopedic limitations to exercise
* Weight loss in the previous 3 months
Minimum Eligible Age

25 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Missouri-Columbia

OTHER

Sponsor Role lead

Responsible Party

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Jill Kanaley

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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Heden TD, Liu Y, Kanaley JA. A comparison of adipose tissue interstitial glucose and venous blood glucose during postprandial resistance exercise in patients with type 2 diabetes. J Appl Physiol (1985). 2018 Apr 1;124(4):1054-1061. doi: 10.1152/japplphysiol.00475.2017. Epub 2017 Sep 28.

Reference Type DERIVED
PMID: 28970202 (View on PubMed)

Other Identifiers

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exertime

Identifier Type: -

Identifier Source: org_study_id

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