Metabolism Des LAM

NCT ID: NCT02176109

Last Updated: 2014-06-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2013-06-30

Study Completion Date

2018-06-30

Brief Summary

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In this study, the investigators study the prognostic role of oxidative stress metabolism and iron in Acute myeloid leukemia.

Detailed Description

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Primary goal of this study is to Evaluate the characteristics of regulatory networks of iron and redox balance in leukemic cells, to study the correlations between the prognosis of AML patients (in terms of response to induction chemotherapy and survival i) and metabolism of these markers. Secondary ones areto assess the impact of induction therapy on markers of oxidative stress and to correlate biological iron and redox metabolism with the molecular status of patients (eg Flt3/IDH/CEBPA/NPM...).

Eligibility criteria are patients at diagnostic of de novo acute myeloid leukemia (promyelocytic excluded) aged from 18 to 100 years.

Conditions

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Iron Acute Myeloid Leukemia Diagnosis Oxydative Stress

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

de novo acute myeloid leukemic patient from 18 years to 99 years at diagnosis

Exclusion Criteria

age under 18 years promelocytic leukemia secondary leukemia
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Grenoble

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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University Hospital Grenoble

Grenoble, Isere, France

Site Status RECRUITING

Countries

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France

Central Contacts

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pascal mossuz, phd

Role: CONTACT

Facility Contacts

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pascal mossuz, phd

Role: primary

0033476763220

Other Identifiers

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Métabolismes des LAM

Identifier Type: REGISTRY

Identifier Source: secondary_id

gre-lam-fer

Identifier Type: -

Identifier Source: org_study_id

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