Short-term Working Memory and Executive Training

NCT ID: NCT02168166

Last Updated: 2018-04-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2014-05-31

Study Completion Date

2017-06-30

Brief Summary

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Cognitive remediation (CR) therapies refer to a number of recent developments to use behavioural strategies to improve neurocognitive abilities and improve everyday functioning in mental disorders such as schizophrenia, bipolar disorder, and depression. In this study, we aim to examine whether we can observe CR effects on measures of neuroplasticity, cognition, and functioning when using a rigorous control comparison group. We hypothesize that the active group will exhibit improvements in executive functioning composite scores, improved EEG theta-gamma frequency modulation, and increased EEG alpha power compared to the placebo group.

Detailed Description

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Conditions

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Psychotic Disorders

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants

Study Groups

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Executive Function Training

Two weeks of training of cognitive domain of executive functioning

Using online program (Scientific Brain Training Pro)

Four exercises

Group Type ACTIVE_COMPARATOR

Executive Function Training

Intervention Type BEHAVIORAL

Placebo Training

Two weeks of training with exercises not affecting working memory, information processing speed, or cognitive load

Exercises maintain other traditional progressive aspects to preserve appearance of dynamic titration of difficulty levels

Using online program (Scientific Brain Training Pro)

Four exercises

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type BEHAVIORAL

Placebo version of executive function training

Interventions

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Executive Function Training

Intervention Type BEHAVIORAL

Placebo

Placebo version of executive function training

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* diagnosis of a chronic mental disorder (defined herein as bipolar disorder, major depressive disorder, or a schizophrenia-spectrum disorder)
* between the ages of 18 and 65
* speak and read fluent English
* able to use a computer

Exclusion Criteria

* active substance abuse or dependence diagnosis
* sensory or motor issues that would preclude completion of study procedures
* enrollment in a cognitive remediation program or use of cognitive training programs (e.g. lumosity.com) within the past 6 months
Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Queen's University

OTHER

Sponsor Role lead

Responsible Party

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Dr. Christopher Bowie

Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Christopher Bowie, PhD, CPsych

Role: PRINCIPAL_INVESTIGATOR

Queen's University

Locations

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Queen's University

Kingston, Ontario, Canada

Site Status

Countries

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Canada

Other Identifiers

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GPSYC-651-14

Identifier Type: -

Identifier Source: org_study_id

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